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Case Report: Complete Necrosis of a Large Adrenocortical Cancer and Liver Metastases Achieved by Selective Arterial Embolization: A Case Study and Review of Literature

There is very limited experience regarding the interventional radiological treatment of adrenocortical cancer (ACC). We present the case of a 57-year-old female patient with a large, potentially unresectable left-sided ACC and two hepatic metastases. Both liver tumors were effectively treated by tra...

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Autores principales: Huszty, Gergely, Doros, Attila, Farkas, Katalin, Kóbori, László, Reismann, Péter, Tőke, Judit, Tóth, Miklós, Igaz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121102/
https://www.ncbi.nlm.nih.gov/pubmed/33995288
http://dx.doi.org/10.3389/fendo.2021.677187
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author Huszty, Gergely
Doros, Attila
Farkas, Katalin
Kóbori, László
Reismann, Péter
Tőke, Judit
Tóth, Miklós
Igaz, Peter
author_facet Huszty, Gergely
Doros, Attila
Farkas, Katalin
Kóbori, László
Reismann, Péter
Tőke, Judit
Tóth, Miklós
Igaz, Peter
author_sort Huszty, Gergely
collection PubMed
description There is very limited experience regarding the interventional radiological treatment of adrenocortical cancer (ACC). We present the case of a 57-year-old female patient with a large, potentially unresectable left-sided ACC and two hepatic metastases. Both liver tumors were effectively treated by trans-arterial embolization (TAE), followed by TAE of the bulky primary tumor as a life-saving intervention necessitated by severe intratumoral bleeding. Surgical removal of the primary tumor revealed complete necrosis. The patient is considered tumor free after 3.5 years. To the best of our knowledge, this is the first report to show that even a primary ACC may be completely ablated by selective embolization, and the fourth to prove the curative potential of liver TAE for ACC metastases. This case highlights the potential of selective embolization in ACC treatment.
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spelling pubmed-81211022021-05-15 Case Report: Complete Necrosis of a Large Adrenocortical Cancer and Liver Metastases Achieved by Selective Arterial Embolization: A Case Study and Review of Literature Huszty, Gergely Doros, Attila Farkas, Katalin Kóbori, László Reismann, Péter Tőke, Judit Tóth, Miklós Igaz, Peter Front Endocrinol (Lausanne) Endocrinology There is very limited experience regarding the interventional radiological treatment of adrenocortical cancer (ACC). We present the case of a 57-year-old female patient with a large, potentially unresectable left-sided ACC and two hepatic metastases. Both liver tumors were effectively treated by trans-arterial embolization (TAE), followed by TAE of the bulky primary tumor as a life-saving intervention necessitated by severe intratumoral bleeding. Surgical removal of the primary tumor revealed complete necrosis. The patient is considered tumor free after 3.5 years. To the best of our knowledge, this is the first report to show that even a primary ACC may be completely ablated by selective embolization, and the fourth to prove the curative potential of liver TAE for ACC metastases. This case highlights the potential of selective embolization in ACC treatment. Frontiers Media S.A. 2021-04-30 /pmc/articles/PMC8121102/ /pubmed/33995288 http://dx.doi.org/10.3389/fendo.2021.677187 Text en Copyright © 2021 Huszty, Doros, Farkas, Kóbori, Reismann, Tőke, Tóth and Igaz https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Huszty, Gergely
Doros, Attila
Farkas, Katalin
Kóbori, László
Reismann, Péter
Tőke, Judit
Tóth, Miklós
Igaz, Peter
Case Report: Complete Necrosis of a Large Adrenocortical Cancer and Liver Metastases Achieved by Selective Arterial Embolization: A Case Study and Review of Literature
title Case Report: Complete Necrosis of a Large Adrenocortical Cancer and Liver Metastases Achieved by Selective Arterial Embolization: A Case Study and Review of Literature
title_full Case Report: Complete Necrosis of a Large Adrenocortical Cancer and Liver Metastases Achieved by Selective Arterial Embolization: A Case Study and Review of Literature
title_fullStr Case Report: Complete Necrosis of a Large Adrenocortical Cancer and Liver Metastases Achieved by Selective Arterial Embolization: A Case Study and Review of Literature
title_full_unstemmed Case Report: Complete Necrosis of a Large Adrenocortical Cancer and Liver Metastases Achieved by Selective Arterial Embolization: A Case Study and Review of Literature
title_short Case Report: Complete Necrosis of a Large Adrenocortical Cancer and Liver Metastases Achieved by Selective Arterial Embolization: A Case Study and Review of Literature
title_sort case report: complete necrosis of a large adrenocortical cancer and liver metastases achieved by selective arterial embolization: a case study and review of literature
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121102/
https://www.ncbi.nlm.nih.gov/pubmed/33995288
http://dx.doi.org/10.3389/fendo.2021.677187
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