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Brain endothelial tricellular junctions as novel sites for T cell diapedesis across the blood–brain barrier

The migration of activated T cells across the blood–brain barrier (BBB) is a critical step in central nervous system (CNS) immune surveillance and inflammation. Whereas T cell diapedesis across the intact BBB seems to occur preferentially through the BBB cellular junctions, impaired BBB integrity du...

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Detalles Bibliográficos
Autores principales: Castro Dias, Mariana, Odriozola Quesada, Adolfo, Soldati, Sasha, Bösch, Fabio, Gruber, Isabelle, Hildbrand, Tobias, Sönmez, Derya, Khire, Tejas, Witz, Guillaume, McGrath, James L., Piontek, Jörg, Kondoh, Masuo, Deutsch, Urban, Zuber, Benoît, Engelhardt, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121105/
https://www.ncbi.nlm.nih.gov/pubmed/33912914
http://dx.doi.org/10.1242/jcs.253880