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Thromboprophylaxis in Intramedullary Limb Lengthening Surgery

AIM: The use of intramedullary lengthening devices is becoming increasingly popular. There are limited data regarding the incidence of venous thromboembolism following intramedullary lengthening surgery and no reports or guidance for current practice on use of thromboprophylaxis. Following a case of...

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Autores principales: Iliadis, Alexios D, Timms, Anna, Fugazzotto, Sharron, Edel, Penina, Britten, Simon, Wright, Jonathan, Goodier, David, Calder, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121112/
https://www.ncbi.nlm.nih.gov/pubmed/34025795
http://dx.doi.org/10.5005/jp-journals-10080-1505
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author Iliadis, Alexios D
Timms, Anna
Fugazzotto, Sharron
Edel, Penina
Britten, Simon
Wright, Jonathan
Goodier, David
Calder, Peter
author_facet Iliadis, Alexios D
Timms, Anna
Fugazzotto, Sharron
Edel, Penina
Britten, Simon
Wright, Jonathan
Goodier, David
Calder, Peter
author_sort Iliadis, Alexios D
collection PubMed
description AIM: The use of intramedullary lengthening devices is becoming increasingly popular. There are limited data regarding the incidence of venous thromboembolism following intramedullary lengthening surgery and no reports or guidance for current practice on use of thromboprophylaxis. Following a case of post-operative deep vein thrombosis in our institution, we felt that it is important to assess best practice. We conducted a national survey to collect data that would describe current practice and help develop consensus for treatment. MATERIALS AND METHODS: We identified surgeons across the UK that perform adult intramedullary limb lengthening through the British Limb Reconstruction Society membership and a Precise Users database. Surgeons were contacted and asked to respond to an online survey. Responses to thromboprophylaxis regimes employed in their practice and cases of venous thromboembolism were collated. RESULTS: 24 out of 54 surgeons identified responded with a total of 454 cases of adult intramedullary lengthening (352 femoral and 102 tibial nails) performed over a five year period (January 2015–January 2020). Only one case of deep venous thrombosis (DVT) following femoral lengthening was reported. There is wide variability in practice both in terms of thromboprophylaxis risk assessment, choice of medications and duration of treatment. The vast majority of surgeons (85%) felt that there was insufficient evidence available to guide their practice. CONCLUSIONS: Intramedullary lengthening is a surgical treatment growing in popularity. There are limited data available to guide decision-making regarding aspects of treatment such as thromboprophylaxis. This is reflected in the wide variation in practice reported in this study. There are both a need and a desire to gather data that will allow us to come to a consensus and to guide safe practice. CLINICAL SIGNIFICANCE: Venous thromboembolism is a potential complication of lower limb lengthening surgery. We report on national incidence and current practices of thromboprophylaxis to allow for informed decision-making and help develop consensus for best practice. HOW TO CITE THIS ARTICLE: Iliadis AD, Timms A, Fugazzotto S, et al. Thromboprophylaxis in Intramedullary Limb Lengthening Surgery. Strategies Trauma Limb Reconstr 2020;15(3):151-156.
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spelling pubmed-81211122021-05-20 Thromboprophylaxis in Intramedullary Limb Lengthening Surgery Iliadis, Alexios D Timms, Anna Fugazzotto, Sharron Edel, Penina Britten, Simon Wright, Jonathan Goodier, David Calder, Peter Strategies Trauma Limb Reconstr Original Article AIM: The use of intramedullary lengthening devices is becoming increasingly popular. There are limited data regarding the incidence of venous thromboembolism following intramedullary lengthening surgery and no reports or guidance for current practice on use of thromboprophylaxis. Following a case of post-operative deep vein thrombosis in our institution, we felt that it is important to assess best practice. We conducted a national survey to collect data that would describe current practice and help develop consensus for treatment. MATERIALS AND METHODS: We identified surgeons across the UK that perform adult intramedullary limb lengthening through the British Limb Reconstruction Society membership and a Precise Users database. Surgeons were contacted and asked to respond to an online survey. Responses to thromboprophylaxis regimes employed in their practice and cases of venous thromboembolism were collated. RESULTS: 24 out of 54 surgeons identified responded with a total of 454 cases of adult intramedullary lengthening (352 femoral and 102 tibial nails) performed over a five year period (January 2015–January 2020). Only one case of deep venous thrombosis (DVT) following femoral lengthening was reported. There is wide variability in practice both in terms of thromboprophylaxis risk assessment, choice of medications and duration of treatment. The vast majority of surgeons (85%) felt that there was insufficient evidence available to guide their practice. CONCLUSIONS: Intramedullary lengthening is a surgical treatment growing in popularity. There are limited data available to guide decision-making regarding aspects of treatment such as thromboprophylaxis. This is reflected in the wide variation in practice reported in this study. There are both a need and a desire to gather data that will allow us to come to a consensus and to guide safe practice. CLINICAL SIGNIFICANCE: Venous thromboembolism is a potential complication of lower limb lengthening surgery. We report on national incidence and current practices of thromboprophylaxis to allow for informed decision-making and help develop consensus for best practice. HOW TO CITE THIS ARTICLE: Iliadis AD, Timms A, Fugazzotto S, et al. Thromboprophylaxis in Intramedullary Limb Lengthening Surgery. Strategies Trauma Limb Reconstr 2020;15(3):151-156. Jaypee Brothers Medical Publishing 2020 /pmc/articles/PMC8121112/ /pubmed/34025795 http://dx.doi.org/10.5005/jp-journals-10080-1505 Text en Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd. https://creativecommons.org/licenses/by-nc/4.0/© Jaypee Brothers Medical Publishers. 2020 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated.
spellingShingle Original Article
Iliadis, Alexios D
Timms, Anna
Fugazzotto, Sharron
Edel, Penina
Britten, Simon
Wright, Jonathan
Goodier, David
Calder, Peter
Thromboprophylaxis in Intramedullary Limb Lengthening Surgery
title Thromboprophylaxis in Intramedullary Limb Lengthening Surgery
title_full Thromboprophylaxis in Intramedullary Limb Lengthening Surgery
title_fullStr Thromboprophylaxis in Intramedullary Limb Lengthening Surgery
title_full_unstemmed Thromboprophylaxis in Intramedullary Limb Lengthening Surgery
title_short Thromboprophylaxis in Intramedullary Limb Lengthening Surgery
title_sort thromboprophylaxis in intramedullary limb lengthening surgery
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121112/
https://www.ncbi.nlm.nih.gov/pubmed/34025795
http://dx.doi.org/10.5005/jp-journals-10080-1505
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