Validation of protein arginine methyltransferase 5 (PRMT5) as a candidate therapeutic target in the spontaneous canine model of non-Hodgkin lymphoma

Non-Hodgkin lymphoma (NHL) is a heterogeneous group of blood cancers arising in lymphoid tissues that commonly effects both humans and dogs. Protein arginine methyltransferase 5 (PRMT5), an enzyme that catalyzes the symmetric di-methylation of arginine residues, is frequently overexpressed and dysre...

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Detalles Bibliográficos
Autores principales: Sloan, Shelby L., Renaldo, Kyle A., Long, Mackenzie, Chung, Ji-Hyun, Courtney, Lindsay E., Shilo, Konstantin, Youssef, Youssef, Schlotter, Sarah, Brown, Fiona, Klamer, Brett G., Zhang, Xiaoli, Yilmaz, Ayse S., Ozer, Hatice G., Valli, Victor E., Vaddi, Kris, Scherle, Peggy, Alinari, Lapo, Kisseberth, William C., Baiocchi, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121334/
https://www.ncbi.nlm.nih.gov/pubmed/33989303
http://dx.doi.org/10.1371/journal.pone.0250839

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