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Circulating neprilysin hypothesis: A new opportunity for sacubitril/valsartan in patients with heart failure and preserved ejection fraction?

BACKGROUND: Circulating Neprilysin (sNEP) has emerged as a potential prognostic biomarker in heart failure (HF). In PARAGON-HF benefit of sacubitril/valsartan was only observed in patients with left ventricular ejection fraction (LVEF) ≤57%. We aimed to assess the prognostic value of sNEP in outpati...

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Detalles Bibliográficos
Autores principales:	Lupón, Josep, Santiago-Vacas, Evelyn, Cediel, Germán, Codina, Pau, Domingo, Mar, Revuelta-López, Elena, Zamora, Elisabet, Spitaleri, Giosafat, Santesmases, Javier, Núñez, Julio, Bayes-Genis, Antoni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121351/ https://www.ncbi.nlm.nih.gov/pubmed/33989294 http://dx.doi.org/10.1371/journal.pone.0249674

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