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Cardiac cell type–specific gene regulatory programs and disease risk association
Misregulated gene expression in human hearts can result in cardiovascular diseases that are leading causes of mortality worldwide. However, the limited information on the genomic location of candidate cis-regulatory elements (cCREs) such as enhancers and promoters in distinct cardiac cell types has...
Autores principales: | Hocker, James D., Poirion, Olivier B., Zhu, Fugui, Buchanan, Justin, Zhang, Kai, Chiou, Joshua, Wang, Tsui-Min, Zhang, Qingquan, Hou, Xiaomeng, Li, Yang E., Zhang, Yanxiao, Farah, Elie N., Wang, Allen, McCulloch, Andrew D., Gaulton, Kyle J., Ren, Bing, Chi, Neil C., Preissl, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121433/ https://www.ncbi.nlm.nih.gov/pubmed/33990324 http://dx.doi.org/10.1126/sciadv.abf1444 |
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