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IL-33 promotes innate lymphoid cell-dependent IFN-γ production required for innate immunity to Toxoplasma gondii

IL-33 is an alarmin required for resistance to the parasite Toxoplasma gondii, but its role in innate resistance to this organism is unclear. Infection with T. gondii promotes increased stromal cell expression of IL-33, and levels of parasite replication correlate with release of IL-33 in affected t...

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Detalles Bibliográficos
Autores principales: Clark, Joseph T, Christian, David A, Gullicksrud, Jodi A, Perry, Joseph A, Park, Jeongho, Jacquet, Maxime, Tarrant, James C, Radaelli, Enrico, Silver, Jonathan, Hunter, Christopher A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121546/
https://www.ncbi.nlm.nih.gov/pubmed/33929319
http://dx.doi.org/10.7554/eLife.65614