Receptor-mediated mitophagy regulates EPO production and protects against renal anemia

Erythropoietin (EPO) drives erythropoiesis and is secreted mainly by the kidney upon hypoxic or anemic stress. The paucity of EPO production in renal EPO-producing cells (REPs) causes renal anemia, one of the most common complications of chronic nephropathies. Although mitochondrial dysfunction is c...

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Detalles Bibliográficos
Autores principales: Geng, Guangfeng, Liu, Jinhua, Xu, Changlu, Pei, Yandong, Chen, Linbo, Mu, Chenglong, Wang, Ding, Gao, Jie, Li, Yue, Liang, Jing, Zhao, Tian, Zhang, Chuanmei, Zhou, Jiaxi, Chen, Quan, Zhu, Yushan, Shi, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121547/
https://www.ncbi.nlm.nih.gov/pubmed/33942716
http://dx.doi.org/10.7554/eLife.64480

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