trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction

During X chromosome inactivation, many chromatin changes occur on the future inactive X chromosome, including acquisition of a variety of repressive covalent histone modifications, heterochromatin protein associations, and DNA methylation of promoters. Here, we summarize trans-acting factors and cis...

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Detalles Bibliográficos
Autores principales: Sun, Zhuo, Fan, Jinbo, Zhao, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121581/
https://www.ncbi.nlm.nih.gov/pubmed/34035662
http://dx.doi.org/10.1155/2021/6683460
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author Sun, Zhuo
Fan, Jinbo
Zhao, Yufeng
author_facet Sun, Zhuo
Fan, Jinbo
Zhao, Yufeng
author_sort Sun, Zhuo
collection PubMed
description During X chromosome inactivation, many chromatin changes occur on the future inactive X chromosome, including acquisition of a variety of repressive covalent histone modifications, heterochromatin protein associations, and DNA methylation of promoters. Here, we summarize trans-acting factors and cis elements that have been shown to be involved in the human inactive X chromosome organization and compaction.
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spelling pubmed-81215812021-05-24 trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction Sun, Zhuo Fan, Jinbo Zhao, Yufeng Genet Res (Camb) Review Article During X chromosome inactivation, many chromatin changes occur on the future inactive X chromosome, including acquisition of a variety of repressive covalent histone modifications, heterochromatin protein associations, and DNA methylation of promoters. Here, we summarize trans-acting factors and cis elements that have been shown to be involved in the human inactive X chromosome organization and compaction. Hindawi 2021-05-07 /pmc/articles/PMC8121581/ /pubmed/34035662 http://dx.doi.org/10.1155/2021/6683460 Text en Copyright © 2021 Zhuo Sun et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Sun, Zhuo
Fan, Jinbo
Zhao, Yufeng
trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction
title trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction
title_full trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction
title_fullStr trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction
title_full_unstemmed trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction
title_short trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction
title_sort trans-acting factors and cis elements involved in the human inactive x chromosome organization and compaction
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121581/
https://www.ncbi.nlm.nih.gov/pubmed/34035662
http://dx.doi.org/10.1155/2021/6683460
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AT zhaoyufeng transactingfactorsandciselementsinvolvedinthehumaninactivexchromosomeorganizationandcompaction

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