Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration

Pantothenate kinase-associated neurodegeneration (PKAN) is a rare disorder associated with brain iron accumulation caused by a recessive mutation in pantothenate kinase 2 gene (PANK2). We present a case of an 11 year-old boy presenting extrapyramidal signs and developmental regression. T2-weighted i...

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Autores principales: Choayb, S., Adil, H., Ali Mohamed, Daoud, Allali, N., Chat, L., El Haddad, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121601/
https://www.ncbi.nlm.nih.gov/pubmed/34040814
http://dx.doi.org/10.1155/2021/6633217
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author Choayb, S.
Adil, H.
Ali Mohamed, Daoud
Allali, N.
Chat, L.
El Haddad, S.
author_facet Choayb, S.
Adil, H.
Ali Mohamed, Daoud
Allali, N.
Chat, L.
El Haddad, S.
author_sort Choayb, S.
collection PubMed
description Pantothenate kinase-associated neurodegeneration (PKAN) is a rare disorder associated with brain iron accumulation caused by a recessive mutation in pantothenate kinase 2 gene (PANK2). We present a case of an 11 year-old boy presenting extrapyramidal signs and developmental regression. T2-weighted images showed the classic eye of the tiger sign seen in pantothenate kinase-associated neurodegeneration.
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spelling pubmed-81216012021-05-25 Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration Choayb, S. Adil, H. Ali Mohamed, Daoud Allali, N. Chat, L. El Haddad, S. Case Rep Radiol Case Report Pantothenate kinase-associated neurodegeneration (PKAN) is a rare disorder associated with brain iron accumulation caused by a recessive mutation in pantothenate kinase 2 gene (PANK2). We present a case of an 11 year-old boy presenting extrapyramidal signs and developmental regression. T2-weighted images showed the classic eye of the tiger sign seen in pantothenate kinase-associated neurodegeneration. Hindawi 2021-05-07 /pmc/articles/PMC8121601/ /pubmed/34040814 http://dx.doi.org/10.1155/2021/6633217 Text en Copyright © 2021 S. Choayb et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Choayb, S.
Adil, H.
Ali Mohamed, Daoud
Allali, N.
Chat, L.
El Haddad, S.
Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration
title Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration
title_full Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration
title_fullStr Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration
title_full_unstemmed Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration
title_short Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration
title_sort eye of the tiger sign in pantothenate kinase-associated neurodegeneration
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121601/
https://www.ncbi.nlm.nih.gov/pubmed/34040814
http://dx.doi.org/10.1155/2021/6633217
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