A Novel pH-Sensitive Multifunctional DNA Nanomedicine: An Enhanced and Harmless GD2 Aptamer-Mediated Strategy for Guiding Neuroblastoma Antitumor Therapy

BACKGROUND: GD2 is a mainstream biomarker for neuroblastoma (NB)-targeted therapy. Current anti-GD2 therapeutics exhibit several side effects since GD2 is also expressed at low levels on normal cells. Thus, current anti-GD2 therapeutics can be compromised by the coexistence of the target receptor on...

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Detalles Bibliográficos
Autores principales: Zhang, Liyu, Wang, Meng, Zhu, Zeen, Ding, Chenxi, Chen, Shengquan, Wu, Haibin, Yang, Ying, Che, Fengyu, Li, Qiao, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121684/
https://www.ncbi.nlm.nih.gov/pubmed/34007175
http://dx.doi.org/10.2147/IJN.S302450

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