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The MicroRNA miR-696 is regulated by SNARK and reduces mitochondrial activity in mouse skeletal muscle through Pgc1α inhibition
OBJECTIVE: MicroRNAs (miRNA) are known to regulate the expression of genes involved in several physiological processes including metabolism, mitochondrial biogenesis, proliferation, differentiation, and cell death. METHODS: Using “in silico” analyses, we identified 219 unique miRNAs that potentially...
Autores principales: | Queiroz, André L., Lessard, Sarah J., Ouchida, Amanda T., Araujo, Hygor N., Gonçalves, Dawit A., Simões Fróes Guimarães, Dimitrius Santiago P., Teodoro, Bruno G., So, Kawai, Espreafico, Enilza M., Hirshman, Michael F., Alberici, Luciane C., Kettelhut, Isis do Carmo, Goodyear, Laurie J., Silveira, Leonardo R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121711/ https://www.ncbi.nlm.nih.gov/pubmed/33812060 http://dx.doi.org/10.1016/j.molmet.2021.101226 |
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