Peptidomics of enteroendocrine cells and characterisation of potential effects of a novel preprogastrin derived-peptide on glucose tolerance in lean mice

OBJECTIVES: To analyse the peptidomics of mouse enteroendocrine cells (EECs) and human gastrointestinal (GI) tissue and identify novel gut derived peptides. METHODS: High resolution nano-flow liquid chromatography mass spectrometry (LC–MS/MS) was performed on (i) flow-cytometry purified NeuroD1 posi...

Descripción completa

Detalles Bibliográficos
Autores principales: Galvin, Sam G., Larraufie, Pierre, Kay, Richard G., Pitt, Haidee, Bernard, Elise, McGavigan, Anne K., Brant, Helen, Hood, John, Sheldrake, Laura, Conder, Shannon, Atherton-Kemp, Dawn, Lu, Van B., O’Flaherty, Elisabeth A.A., Roberts, Geoffrey P., Ämmälä, Carina, Jermutus, Lutz, Baker, David, Gribble, Fiona M., Reimann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Inc 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121762/
https://www.ncbi.nlm.nih.gov/pubmed/33744371
http://dx.doi.org/10.1016/j.peptides.2021.170532

Ejemplares similares

Ejemplares similares