Cargando…
A robust protocol for the generation of human midbrain organoids
The lack of advanced in vitro models recapitulating the human brain complexity is still a major obstacle in brain development and neurological disease research. Here, we describe a robust protocol to derive human midbrain organoids from neuroepithelial stem cells. These complex 3D models are charact...
Autores principales: | Zagare, Alise, Gobin, Matthieu, Monzel, Anna S., Schwamborn, Jens C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121770/ https://www.ncbi.nlm.nih.gov/pubmed/34027482 http://dx.doi.org/10.1016/j.xpro.2021.100524 |
Ejemplares similares
-
Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-p.Gly2019Ser-associated gene expression
por: Zagare, Alise, et al.
Publicado: (2022) -
Protocol for generating reproducible miniaturized controlled midbrain organoids
por: Chen, Muwan, et al.
Publicado: (2023) -
Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells
por: Monzel, Anna S., et al.
Publicado: (2017) -
Modeling Parkinson’s disease in midbrain-like organoids
por: Smits, Lisa M., et al.
Publicado: (2019) -
Midbrain Organoids: A New Tool to Investigate Parkinson’s Disease
por: Smits, Lisa Maria, et al.
Publicado: (2020)