Interplay between transforming growth factor-β and Nur77 in dual regulations of inhibitor of differentiation 1 for colonic tumorigenesis

The paradoxical roles of transforming growth factor-β (TGFβ) signaling and nuclear receptor Nur77 in colon cancer development are known but the underlying mechanisms remain obscure. Inhibitor of differentiation 1 (ID1) is a target gene of TGFβ and a key promoter for colon cancer progression. Here, w...

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Detalles Bibliográficos
Autores principales: Niu, Boning, Liu, Jie, Lv, Ben, Lin, Jiacheng, Li, Xin, Wu, Chunxiao, Jiang, Xiaohua, Zeng, Zhiping, Zhang, Xiao-kun, Zhou, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121807/
https://www.ncbi.nlm.nih.gov/pubmed/33990575
http://dx.doi.org/10.1038/s41467-021-23048-5

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