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Time-resolved spectroscopic and electrophysiological data reveal insights in the gating mechanism of anion channelrhodopsin

Channelrhodopsins are widely used in optogenetic applications. High photocurrents and low current inactivation levels are desirable. Two parallel photocycles evoked by different retinal conformations cause cation-conducting channelrhodopsin-2 (CrChR2) inactivation: one with efficient conductivity; o...

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Detalles Bibliográficos
Autores principales:	Dreier, Max-Aylmer, Althoff, Philipp, Norahan, Mohamad Javad, Tennigkeit, Stefan Alexander, El-Mashtoly, Samir F., Lübben, Mathias, Kötting, Carsten, Rudack, Till, Gerwert, Klaus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121809/ https://www.ncbi.nlm.nih.gov/pubmed/33990694 http://dx.doi.org/10.1038/s42003-021-02101-5

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