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Exploring the feasibility of using real-world data from a large clinical data research network to simulate clinical trials of Alzheimer’s disease

In this study, we explored the feasibility of using real-world data (RWD) from a large clinical research network to simulate real-world clinical trials of Alzheimer’s disease (AD). The target trial (i.e., NCT00478205) is a Phase III double-blind, parallel-group trial that compared the 23 mg donepezi...

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Detalles Bibliográficos
Autores principales: Chen, Zhaoyi, Zhang, Hansi, Guo, Yi, George, Thomas J., Prosperi, Mattia, Hogan, William R., He, Zhe, Shenkman, Elizabeth A., Wang, Fei, Bian, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121837/
https://www.ncbi.nlm.nih.gov/pubmed/33990663
http://dx.doi.org/10.1038/s41746-021-00452-1