NMDAR-dependent long-term depression is associated with increased short term plasticity through autophagy mediated loss of PSD-95

Long-term depression (LTD) of synaptic strength can take multiple forms and contribute to circuit remodeling, memory encoding or erasure. The generic term LTD encompasses various induction pathways, including activation of NMDA, mGlu or P2X receptors. However, the associated specific molecular mecha...

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Detalles Bibliográficos
Autores principales: Compans, Benjamin, Camus, Come, Kallergi, Emmanouela, Sposini, Silvia, Martineau, Magalie, Butler, Corey, Kechkar, Adel, Klaassen, Remco V., Retailleau, Natacha, Sejnowski, Terrence J., Smit, August B., Sibarita, Jean-Baptiste, Bartol, Thomas M., Perrais, David, Nikoletopoulou, Vassiliki, Choquet, Daniel, Hosy, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121912/
https://www.ncbi.nlm.nih.gov/pubmed/33990590
http://dx.doi.org/10.1038/s41467-021-23133-9

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