Quality control of protein reagents for the improvement of research data reproducibility

Proteins and peptides are amongst the most widely used research reagents but often their quality is inadequate and can result in poor data reproducibility. Here we propose a simple set of guidelines that, when correctly applied to protein reagents should provide more reliable experimental data.

Detalles Bibliográficos
Autores principales: de Marco, Ario, Berrow, Nick, Lebendiker, Mario, Garcia-Alai, Maria, Knauer, Stefan H., Lopez-Mendez, Blanca, Matagne, André, Parret, Annabel, Remans, Kim, Uebel, Stephan, Raynal, Bertrand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121922/
https://www.ncbi.nlm.nih.gov/pubmed/33990604
http://dx.doi.org/10.1038/s41467-021-23167-z
Descripción
Sumario:Proteins and peptides are amongst the most widely used research reagents but often their quality is inadequate and can result in poor data reproducibility. Here we propose a simple set of guidelines that, when correctly applied to protein reagents should provide more reliable experimental data.

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