Quality control of protein reagents for the improvement of research data reproducibility

Proteins and peptides are amongst the most widely used research reagents but often their quality is inadequate and can result in poor data reproducibility. Here we propose a simple set of guidelines that, when correctly applied to protein reagents should provide more reliable experimental data.

Detalles Bibliográficos
Autores principales: de Marco, Ario, Berrow, Nick, Lebendiker, Mario, Garcia-Alai, Maria, Knauer, Stefan H., Lopez-Mendez, Blanca, Matagne, André, Parret, Annabel, Remans, Kim, Uebel, Stephan, Raynal, Bertrand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121922/
https://www.ncbi.nlm.nih.gov/pubmed/33990604
http://dx.doi.org/10.1038/s41467-021-23167-z
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author de Marco, Ario
Berrow, Nick
Lebendiker, Mario
Garcia-Alai, Maria
Knauer, Stefan H.
Lopez-Mendez, Blanca
Matagne, André
Parret, Annabel
Remans, Kim
Uebel, Stephan
Raynal, Bertrand
author_facet de Marco, Ario
Berrow, Nick
Lebendiker, Mario
Garcia-Alai, Maria
Knauer, Stefan H.
Lopez-Mendez, Blanca
Matagne, André
Parret, Annabel
Remans, Kim
Uebel, Stephan
Raynal, Bertrand
author_sort de Marco, Ario
collection PubMed
description Proteins and peptides are amongst the most widely used research reagents but often their quality is inadequate and can result in poor data reproducibility. Here we propose a simple set of guidelines that, when correctly applied to protein reagents should provide more reliable experimental data.
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spelling pubmed-81219222021-05-18 Quality control of protein reagents for the improvement of research data reproducibility de Marco, Ario Berrow, Nick Lebendiker, Mario Garcia-Alai, Maria Knauer, Stefan H. Lopez-Mendez, Blanca Matagne, André Parret, Annabel Remans, Kim Uebel, Stephan Raynal, Bertrand Nat Commun Comment Proteins and peptides are amongst the most widely used research reagents but often their quality is inadequate and can result in poor data reproducibility. Here we propose a simple set of guidelines that, when correctly applied to protein reagents should provide more reliable experimental data. Nature Publishing Group UK 2021-05-14 /pmc/articles/PMC8121922/ /pubmed/33990604 http://dx.doi.org/10.1038/s41467-021-23167-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Comment
de Marco, Ario
Berrow, Nick
Lebendiker, Mario
Garcia-Alai, Maria
Knauer, Stefan H.
Lopez-Mendez, Blanca
Matagne, André
Parret, Annabel
Remans, Kim
Uebel, Stephan
Raynal, Bertrand
Quality control of protein reagents for the improvement of research data reproducibility
title Quality control of protein reagents for the improvement of research data reproducibility
title_full Quality control of protein reagents for the improvement of research data reproducibility
title_fullStr Quality control of protein reagents for the improvement of research data reproducibility
title_full_unstemmed Quality control of protein reagents for the improvement of research data reproducibility
title_short Quality control of protein reagents for the improvement of research data reproducibility
title_sort quality control of protein reagents for the improvement of research data reproducibility
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121922/
https://www.ncbi.nlm.nih.gov/pubmed/33990604
http://dx.doi.org/10.1038/s41467-021-23167-z
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