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Hypoxic acclimation improves cardiac redox homeostasis and protects heart against ischemia-reperfusion injury through upregulation of O-GlcNAcylation

Ischemia-reperfusion (I/R) injury is detrimental to cardiovascular system. Alteration in glucose metabolism has been recognized as an important adaptive response under hypoxic conditions. However, the biological benefits underlying this metabolic phenotype remain to be elucidated. This study was des...

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Detalles Bibliográficos
Autores principales: Ou, Wei, Liang, Yu, Qin, Yu, Wu, Wei, Xie, Maodi, Zhang, Yabing, Zhang, Yarong, Ji, Liwei, Yu, Haiyang, Li, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121980/
https://www.ncbi.nlm.nih.gov/pubmed/33964586
http://dx.doi.org/10.1016/j.redox.2021.101994