Delineating copy number and clonal substructure in human tumors from single-cell transcriptomes

Single-cell transcriptomic analysis is widely used to study human tumors. However it remains challenging to distinguish normal cell types in the tumor microenvironment from malignant cells and to resolve clonal substructure within the tumor. To address these challenges, we developed an integrative B...

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Detalles Bibliográficos
Autores principales: Gao, Ruli, Bai, Shanshan, Henderson, Ying C., Lin, Yiyun, Schalck, Aislyn, Yan, Yun, Kumar, Tapsi, Hu, Min, Sei, Emi, Davis, Alexander, Wang, Fang, Shaitelman, Simona F., Wang, Jennifer Rui, Chen, Ken, Moulder, Stacy, Lai, Stephen Y., Navin, Nicholas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122019/
https://www.ncbi.nlm.nih.gov/pubmed/33462507
http://dx.doi.org/10.1038/s41587-020-00795-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122019/
https://www.ncbi.nlm.nih.gov/pubmed/33462507
http://dx.doi.org/10.1038/s41587-020-00795-2

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