POINT technology illuminates the processing of polymerase-associated intact nascent transcripts

Mammalian chromatin is the site of both RNA polymerase II (Pol II) transcription and coupled RNA processing. However, molecular details of such co-transcriptional mechanisms remain obscure, partly because of technical limitations in purifying authentic nascent transcripts. We present a new approach...

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Detalles Bibliográficos
Autores principales: Sousa-Luís, Rui, Dujardin, Gwendal, Zukher, Inna, Kimura, Hiroshi, Weldon, Carika, Carmo-Fonseca, Maria, Proudfoot, Nick J., Nojima, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122139/
https://www.ncbi.nlm.nih.gov/pubmed/33735606
http://dx.doi.org/10.1016/j.molcel.2021.02.034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122139/
https://www.ncbi.nlm.nih.gov/pubmed/33735606
http://dx.doi.org/10.1016/j.molcel.2021.02.034

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