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POINT technology illuminates the processing of polymerase-associated intact nascent transcripts
Mammalian chromatin is the site of both RNA polymerase II (Pol II) transcription and coupled RNA processing. However, molecular details of such co-transcriptional mechanisms remain obscure, partly because of technical limitations in purifying authentic nascent transcripts. We present a new approach...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122139/ https://www.ncbi.nlm.nih.gov/pubmed/33735606 http://dx.doi.org/10.1016/j.molcel.2021.02.034 |