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Novel Japanese encephalitis virus NS1-based vaccine: Truncated NS1 fused with E. coli heat labile enterotoxin B subunit

BACKGROUND: Current vaccines against Japanese encephalitis virus (JEV) of flaviviruses have some disadvantages, such as the risk of virulent reversion. Non-structural protein NS1 is conserved among flaviviruses and confers immune protection without the risk of antibody-dependent enhancement (ADE). T...

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Detalles Bibliográficos
Autores principales: Wan, Jiawu, Wang, Ting, Xu, Jing, Ouyang, Tao, Wang, Qianruo, Zhang, Yanni, Weng, Shiqi, Li, Yihan, Wang, Yu, Xin, Xiu, Wang, Xiaoling, Li, Sha, Kong, Lingbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122160/
https://www.ncbi.nlm.nih.gov/pubmed/33971403
http://dx.doi.org/10.1016/j.ebiom.2021.103353