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Novel Japanese encephalitis virus NS1-based vaccine: Truncated NS1 fused with E. coli heat labile enterotoxin B subunit
BACKGROUND: Current vaccines against Japanese encephalitis virus (JEV) of flaviviruses have some disadvantages, such as the risk of virulent reversion. Non-structural protein NS1 is conserved among flaviviruses and confers immune protection without the risk of antibody-dependent enhancement (ADE). T...
Autores principales: | Wan, Jiawu, Wang, Ting, Xu, Jing, Ouyang, Tao, Wang, Qianruo, Zhang, Yanni, Weng, Shiqi, Li, Yihan, Wang, Yu, Xin, Xiu, Wang, Xiaoling, Li, Sha, Kong, Lingbao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122160/ https://www.ncbi.nlm.nih.gov/pubmed/33971403 http://dx.doi.org/10.1016/j.ebiom.2021.103353 |
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