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Deep learning enabled real-time photoacoustic tomography system via single data acquisition channel

Photoacoustic computed tomography (PACT) combines the optical contrast of optical imaging and the penetrability of sonography. In this work, we develop a novel PACT system to provide real-time imaging, which is achieved by a 120-elements ultrasound array only using a single data acquisition (DAQ) ch...

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Autores principales: Lan, Hengrong, Jiang, Daohuai, Gao, Feng, Gao, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122165/
https://www.ncbi.nlm.nih.gov/pubmed/34026492
http://dx.doi.org/10.1016/j.pacs.2021.100270
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author Lan, Hengrong
Jiang, Daohuai
Gao, Feng
Gao, Fei
author_facet Lan, Hengrong
Jiang, Daohuai
Gao, Feng
Gao, Fei
author_sort Lan, Hengrong
collection PubMed
description Photoacoustic computed tomography (PACT) combines the optical contrast of optical imaging and the penetrability of sonography. In this work, we develop a novel PACT system to provide real-time imaging, which is achieved by a 120-elements ultrasound array only using a single data acquisition (DAQ) channel. To reduce the channel number of DAQ, we superimpose 30 nearby channels’ signals together in the analog domain, and shrinking to 4 channels of data (120/30 = 4). Furthermore, a four-to-one delay-line module is designed to combine these four channels’ data into one channel before entering the single-channel DAQ, followed by decoupling the signals after data acquisition. To reconstruct the image from four superimposed 30-channels’ PA signals, we train a dedicated deep learning model to reconstruct the final PA image. In this paper, we present the preliminary results of phantom and in-vivo experiments, which manifests its robust real-time imaging performance. The significance of this novel PACT system is that it dramatically reduces the cost of multi-channel DAQ module (from 120 channels to 1 channel), paving the way to a portable, low-cost and real-time PACT system.
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spelling pubmed-81221652021-05-21 Deep learning enabled real-time photoacoustic tomography system via single data acquisition channel Lan, Hengrong Jiang, Daohuai Gao, Feng Gao, Fei Photoacoustics Research Article Photoacoustic computed tomography (PACT) combines the optical contrast of optical imaging and the penetrability of sonography. In this work, we develop a novel PACT system to provide real-time imaging, which is achieved by a 120-elements ultrasound array only using a single data acquisition (DAQ) channel. To reduce the channel number of DAQ, we superimpose 30 nearby channels’ signals together in the analog domain, and shrinking to 4 channels of data (120/30 = 4). Furthermore, a four-to-one delay-line module is designed to combine these four channels’ data into one channel before entering the single-channel DAQ, followed by decoupling the signals after data acquisition. To reconstruct the image from four superimposed 30-channels’ PA signals, we train a dedicated deep learning model to reconstruct the final PA image. In this paper, we present the preliminary results of phantom and in-vivo experiments, which manifests its robust real-time imaging performance. The significance of this novel PACT system is that it dramatically reduces the cost of multi-channel DAQ module (from 120 channels to 1 channel), paving the way to a portable, low-cost and real-time PACT system. Elsevier 2021-05-05 /pmc/articles/PMC8122165/ /pubmed/34026492 http://dx.doi.org/10.1016/j.pacs.2021.100270 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Lan, Hengrong
Jiang, Daohuai
Gao, Feng
Gao, Fei
Deep learning enabled real-time photoacoustic tomography system via single data acquisition channel
title Deep learning enabled real-time photoacoustic tomography system via single data acquisition channel
title_full Deep learning enabled real-time photoacoustic tomography system via single data acquisition channel
title_fullStr Deep learning enabled real-time photoacoustic tomography system via single data acquisition channel
title_full_unstemmed Deep learning enabled real-time photoacoustic tomography system via single data acquisition channel
title_short Deep learning enabled real-time photoacoustic tomography system via single data acquisition channel
title_sort deep learning enabled real-time photoacoustic tomography system via single data acquisition channel
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122165/
https://www.ncbi.nlm.nih.gov/pubmed/34026492
http://dx.doi.org/10.1016/j.pacs.2021.100270
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