Precision and Immunoprevention Strategies for Tobacco-Related Head and Neck Cancer Chemoprevention

To date, there is no FDA-approved chemoprevention approach for tobacco-related HNSCC. Effective chemoprevention approaches validated in sufficiently powered randomized trials are needed to reduce the incidence and improve survival. In this review, we recap the challenges encountered in past chemopre...

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Detalles Bibliográficos
Autores principales: Centuori, Sara M., Caulin, Carlos, Bauman, Julie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Head and Neck Cancer (JL Geiger, Section Editor)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122210/
https://www.ncbi.nlm.nih.gov/pubmed/33991232
http://dx.doi.org/10.1007/s11864-021-00848-x
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author Centuori, Sara M.
Caulin, Carlos
Bauman, Julie E.
author_facet Centuori, Sara M.
Caulin, Carlos
Bauman, Julie E.
author_sort Centuori, Sara M.
collection PubMed
description To date, there is no FDA-approved chemoprevention approach for tobacco-related HNSCC. Effective chemoprevention approaches validated in sufficiently powered randomized trials are needed to reduce the incidence and improve survival. In this review, we recap the challenges encountered in past chemoprevention trials and discuss emerging approaches, with major focus on green chemoprevention, precision prevention, and immunoprevention. As our current depth of knowledge expands in the arena of cancer immunotherapy, the field of immunoprevention is primed for new discoveries and successes in cancer prevention.
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spelling pubmed-81222102021-05-17 Precision and Immunoprevention Strategies for Tobacco-Related Head and Neck Cancer Chemoprevention Centuori, Sara M. Caulin, Carlos Bauman, Julie E. Curr Treat Options Oncol Head and Neck Cancer (JL Geiger, Section Editor) To date, there is no FDA-approved chemoprevention approach for tobacco-related HNSCC. Effective chemoprevention approaches validated in sufficiently powered randomized trials are needed to reduce the incidence and improve survival. In this review, we recap the challenges encountered in past chemoprevention trials and discuss emerging approaches, with major focus on green chemoprevention, precision prevention, and immunoprevention. As our current depth of knowledge expands in the arena of cancer immunotherapy, the field of immunoprevention is primed for new discoveries and successes in cancer prevention. Springer US 2021-05-15 2021 /pmc/articles/PMC8122210/ /pubmed/33991232 http://dx.doi.org/10.1007/s11864-021-00848-x Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Head and Neck Cancer (JL Geiger, Section Editor)
Centuori, Sara M.
Caulin, Carlos
Bauman, Julie E.
Precision and Immunoprevention Strategies for Tobacco-Related Head and Neck Cancer Chemoprevention
title Precision and Immunoprevention Strategies for Tobacco-Related Head and Neck Cancer Chemoprevention
title_full Precision and Immunoprevention Strategies for Tobacco-Related Head and Neck Cancer Chemoprevention
title_fullStr Precision and Immunoprevention Strategies for Tobacco-Related Head and Neck Cancer Chemoprevention
title_full_unstemmed Precision and Immunoprevention Strategies for Tobacco-Related Head and Neck Cancer Chemoprevention
title_short Precision and Immunoprevention Strategies for Tobacco-Related Head and Neck Cancer Chemoprevention
title_sort precision and immunoprevention strategies for tobacco-related head and neck cancer chemoprevention
topic Head and Neck Cancer (JL Geiger, Section Editor)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122210/
https://www.ncbi.nlm.nih.gov/pubmed/33991232
http://dx.doi.org/10.1007/s11864-021-00848-x
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