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Leisure-Time Physical Activity before and during Pregnancy Is Associated with Improved Insulin Resistance in Late Pregnancy

A total of 83 third trimester pregnant women were recruited to examine the role of pre-pregnancy versus late-pregnancy physical activity on maternal insulin resistance. Principal component analysis plots demonstrated a distinction between the high and low Homeostatic Model Assessment for Insulin Res...

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Autores principales: Cai, Chenxi, Zhang, Zhengxiao, Mcdonald, Samantha, Strom, Cody, Skow, Rachel J., May, Linda E., Steinback, Craig D., Davenport, Margie H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122248/
https://www.ncbi.nlm.nih.gov/pubmed/33919214
http://dx.doi.org/10.3390/ijerph18094413
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author Cai, Chenxi
Zhang, Zhengxiao
Mcdonald, Samantha
Strom, Cody
Skow, Rachel J.
May, Linda E.
Steinback, Craig D.
Davenport, Margie H.
author_facet Cai, Chenxi
Zhang, Zhengxiao
Mcdonald, Samantha
Strom, Cody
Skow, Rachel J.
May, Linda E.
Steinback, Craig D.
Davenport, Margie H.
author_sort Cai, Chenxi
collection PubMed
description A total of 83 third trimester pregnant women were recruited to examine the role of pre-pregnancy versus late-pregnancy physical activity on maternal insulin resistance. Principal component analysis plots demonstrated a distinction between the high and low Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) groups. The variation was driven primarily by exercise prior to and during pregnancy. Specifically, higher levels of physical activity prior to pregnancy was associated with a lower HOMA-IR and is not modified by other variables. Women who were active prior to pregnancy were more active during pregnancy. These results suggest that being active before pregnancy may be a good strategy for mitigating the risk of insulin resistance during late pregnancy.
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spelling pubmed-81222482021-05-16 Leisure-Time Physical Activity before and during Pregnancy Is Associated with Improved Insulin Resistance in Late Pregnancy Cai, Chenxi Zhang, Zhengxiao Mcdonald, Samantha Strom, Cody Skow, Rachel J. May, Linda E. Steinback, Craig D. Davenport, Margie H. Int J Environ Res Public Health Brief Report A total of 83 third trimester pregnant women were recruited to examine the role of pre-pregnancy versus late-pregnancy physical activity on maternal insulin resistance. Principal component analysis plots demonstrated a distinction between the high and low Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) groups. The variation was driven primarily by exercise prior to and during pregnancy. Specifically, higher levels of physical activity prior to pregnancy was associated with a lower HOMA-IR and is not modified by other variables. Women who were active prior to pregnancy were more active during pregnancy. These results suggest that being active before pregnancy may be a good strategy for mitigating the risk of insulin resistance during late pregnancy. MDPI 2021-04-21 /pmc/articles/PMC8122248/ /pubmed/33919214 http://dx.doi.org/10.3390/ijerph18094413 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Cai, Chenxi
Zhang, Zhengxiao
Mcdonald, Samantha
Strom, Cody
Skow, Rachel J.
May, Linda E.
Steinback, Craig D.
Davenport, Margie H.
Leisure-Time Physical Activity before and during Pregnancy Is Associated with Improved Insulin Resistance in Late Pregnancy
title Leisure-Time Physical Activity before and during Pregnancy Is Associated with Improved Insulin Resistance in Late Pregnancy
title_full Leisure-Time Physical Activity before and during Pregnancy Is Associated with Improved Insulin Resistance in Late Pregnancy
title_fullStr Leisure-Time Physical Activity before and during Pregnancy Is Associated with Improved Insulin Resistance in Late Pregnancy
title_full_unstemmed Leisure-Time Physical Activity before and during Pregnancy Is Associated with Improved Insulin Resistance in Late Pregnancy
title_short Leisure-Time Physical Activity before and during Pregnancy Is Associated with Improved Insulin Resistance in Late Pregnancy
title_sort leisure-time physical activity before and during pregnancy is associated with improved insulin resistance in late pregnancy
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122248/
https://www.ncbi.nlm.nih.gov/pubmed/33919214
http://dx.doi.org/10.3390/ijerph18094413
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