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Polycystin-2 Is Required for Chondrocyte Mechanotransduction and Traffics to the Primary Cilium in Response to Mechanical Stimulation
Primary cilia and associated intraflagellar transport are essential for skeletal development, joint homeostasis, and the response to mechanical stimuli, although the mechanisms remain unclear. Polycystin-2 (PC2) is a member of the transient receptor potential polycystic (TRPP) family of cation chann...
Autores principales: | Thompson, Clare L., McFie, Megan, Chapple, J. Paul, Beales, Philip, Knight, Martin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122406/ https://www.ncbi.nlm.nih.gov/pubmed/33919210 http://dx.doi.org/10.3390/ijms22094313 |
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