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Polycystin-2 Is Required for Chondrocyte Mechanotransduction and Traffics to the Primary Cilium in Response to Mechanical Stimulation

Primary cilia and associated intraflagellar transport are essential for skeletal development, joint homeostasis, and the response to mechanical stimuli, although the mechanisms remain unclear. Polycystin-2 (PC2) is a member of the transient receptor potential polycystic (TRPP) family of cation chann...

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Detalles Bibliográficos
Autores principales: Thompson, Clare L., McFie, Megan, Chapple, J. Paul, Beales, Philip, Knight, Martin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122406/
https://www.ncbi.nlm.nih.gov/pubmed/33919210
http://dx.doi.org/10.3390/ijms22094313

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