A Drug Screening Pipeline Using 2D and 3D Patient-Derived In Vitro Models for Pre-Clinical Analysis of Therapy Response in Glioblastoma

Glioblastoma is one of the most common and lethal types of primary brain tumor. Despite aggressive treatment with chemotherapy and radiotherapy, tumor recurrence within 6–9 months is common. To overcome this, more effective therapies targeting cancer cell stemness, invasion, metabolism, cell death r...

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Detalles Bibliográficos
Autores principales: Lenin, Sakthi, Ponthier, Elise, Scheer, Kaitlin G., Yeo, Erica C. F., Tea, Melinda N., Ebert, Lisa M., Oksdath Mansilla, Mariana, Poonnoose, Santosh, Baumgartner, Ulrich, Day, Bryan W., Ormsby, Rebecca J., Pitson, Stuart M., Gomez, Guillermo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122466/
https://www.ncbi.nlm.nih.gov/pubmed/33919246
http://dx.doi.org/10.3390/ijms22094322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122466/
https://www.ncbi.nlm.nih.gov/pubmed/33919246
http://dx.doi.org/10.3390/ijms22094322

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