Splicing factor SRSF1 promotes breast cancer progression via oncogenic splice switching of PTPMT1

BACKGROUND: Intensive evidence has highlighted the effect of aberrant alternative splicing (AS) events on cancer progression when triggered by dysregulation of the SR protein family. Nonetheless, the underlying mechanism in breast cancer (BRCA) remains elusive. Here we sought to explore the molecula...

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Detalles Bibliográficos
Autores principales: Du, Jun-Xian, Luo, Yi-Hong, Zhang, Si-Jia, Wang, Biao, Chen, Cong, Zhu, Gui-Qi, Zhu, Ping, Cai, Cheng-Zhe, Wan, Jing-Lei, Cai, Jia-Liang, Chen, Shi-Ping, Dai, Zhi, Zhu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122567/
https://www.ncbi.nlm.nih.gov/pubmed/33992102
http://dx.doi.org/10.1186/s13046-021-01978-8

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