Cargando…

Pentacyclic Triterpenoids with Nitrogen-Containing Heterocyclic Moiety, Privileged Hybrids in Anticancer Drug Discovery

Pentacyclic triterpenoids are well-known phytochemicals with various biological activities commonly found in plants as secondary metabolites. The wide range of biological activities exhibited by triterpenoids has made them the most valuable sources of pharmacological agents. A number of novel triter...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khwaza, Vuyolwethu, Mlala, Sithenkosi, Oyedeji, Opeoluwa O., Aderibigbe, Blessing A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122576/ https://www.ncbi.nlm.nih.gov/pubmed/33918996 http://dx.doi.org/10.3390/molecules26092401

Ejemplares similares

Antiviral Activities of Oleanolic Acid and Its Analogues
por: Khwaza, Vuyolwethu, et al.
Publicado: (2018)

Ursolic Acid-Based Derivatives as Potential Anti-Cancer Agents: An Update
por: Khwaza, Vuyolwethu, et al.
Publicado: (2020)

Polymer-Based Scaffolds Loaded with Aloe vera Extract for the Treatment of Wounds
por: Alven, Sibusiso, et al.
Publicado: (2021)

Ursolic Acid and Its Derivatives as Bioactive Agents
por: Mlala, Sithenkosi, et al.
Publicado: (2019)

The Presence of a Cyclohexyldiamine Moiety Confers Cytotoxicity to Pentacyclic Triterpenoids
por: Hoenke, Sophie, et al.
Publicado: (2021)

Nanoformulations for Delivery of Pentacyclic Triterpenoids in Anticancer Therapies
por: Kaps, Anna, et al.
Publicado: (2021)

Curcumin and Its Derivatives as Potential Therapeutic Agents in Prostate, Colon and Breast Cancers
por: Mbese, Zintle, et al.
Publicado: (2019)

Semisynthetic Derivatives of Pentacyclic Triterpenes Bearing Heterocyclic Moieties with Therapeutic Potential
por: Nistor, Gabriela, et al.
Publicado: (2022)

Role of Pentacyclic Triterpenoids in Chemoprevention and Anticancer Treatment: An Overview on Targets and Underling Mechanisms
por: Ghante, Mahavir H., et al.
Publicado: (2019)

Pentacyclic Triterpenoid Phytochemicals with Anticancer Activity: Updated Studies on Mechanisms and Targeted Delivery
por: Nistor, Madalina, et al.
Publicado: (2023)

Bioinspired synthesis of pentacyclic onocerane triterpenoids
por: Bartels, Florian, et al.
Publicado: (2017)

New Betulin Derivatives with Nitrogen Heterocyclic Moiety—Synthesis and Anticancer Activity In Vitro
por: Bębenek, Ewa, et al.
Publicado: (2022)

Antidepressant potential of nitrogen-containing heterocyclic moieties: An updated review
por: Siddiqui, Nadeem, et al.
Publicado: (2011)

Synthesis, Anticancer and Antitubercular Properties of New Chalcones and Their Nitrogen-Containing Five-Membered Heterocyclic Hybrids Bearing Sulfonamide Moiety
por: Castaño, Lina Fernanda, et al.
Publicado: (2022)

Variation of salinity and nitrogen concentration affects the pentacyclic triterpenoid inventory of the haloalkaliphilic aerobic methanotrophic bacterium Methylotuvimicrobium alcaliphilum
por: Cordova-Gonzalez, Alexmar, et al.
Publicado: (2021)

In vitro anticancer activity of a pentacyclic triterpenoid via the mitochondrial pathway in bone-invasive oral squamous cell carcinoma
por: Adtani, Pooja Narain, et al.
Publicado: (2021)

Transcriptional Profiles of the Response of Methicillin-Resistant Staphylococcus aureus to Pentacyclic Triterpenoids
por: Chung, Pooi Yin, et al.
Publicado: (2013)

Bauerenol Acetate, the Pentacyclic Triterpenoid from Tabernaemontana longipes, is an Antitrypanosomal Agent
por: Carothers, Simira, et al.
Publicado: (2018)

Pentacyclic Triterpenoids from the Medicinal Herb, Centella asiatica (L.) Urban
por: James, Jacinda T., et al.
Publicado: (2009)

Antibacterial and Synergistic Activity of Pentacyclic Triterpenoids Isolated from Alstonia scholaris
por: Wang, Chao-Min, et al.
Publicado: (2016)

Ursolic Acid—A Pentacyclic Triterpenoid with a Wide Spectrum of Pharmacological Activities
por: Woźniak, Łukasz, et al.
Publicado: (2015)

Pentacyclic Triterpenoids from Sabia discolor Dunn and Their α-Glycosidase Inhibitory Activities
por: Ma, Jin-Hong, et al.
Publicado: (2022)

The pentacyclic triterpenoid phytosterol lupeol promotes antioxidant response in the nematode C. elegans
por: Voia, Anna, et al.
Publicado: (2022)

Synthesis and anticancer activity of podophyllotoxin derivatives with nitrogen-containing heterocycles
por: Yin, Meng, et al.
Publicado: (2023)

Synergistic antimicrobial activity between pentacyclic triterpenoids and antibiotics against Staphylococcus aureus strains
por: Chung, Pooi Yin, et al.
Publicado: (2011)

In Vitro Antioxidant Activity Potential of Lantadene A, a Pentacyclic Triterpenoid of Lantana Plants
por: Grace-Lynn, Chong, et al.
Publicado: (2012)

Neutrophil elastase inhibitory effects of pentacyclic triterpenoids from Eriobotrya japonica (loquat leaves)
por: Zhang, Jie, et al.
Publicado: (2019)

Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the (13)C-NMR Data
por: Camargo, Karen Caroline, et al.
Publicado: (2022)

Metabolite and Gene Expression Analysis Underlying Temporal and Spatial Accumulation of Pentacyclic Triterpenoids in Jujube
por: Wen, Cuiping, et al.
Publicado: (2022)

Pharmacological Features of 18β-Glycyrrhetinic Acid: A Pentacyclic Triterpenoid of Therapeutic Potential
por: Shinu, Pottathil, et al.
Publicado: (2023)

Four New Unusual Pentacyclic Triterpenoids from the Roots of Jasminum sambac (L.) Ait
por: Olatunde, Olagoke Zacchaeus, et al.
Publicado: (2023)

Decoration of A-Ring of a Lupane-Type Triterpenoid with Different Oxygen and Nitrogen Heterocycles
por: Sousa, Joana L. C., et al.
Publicado: (2022)

Nitrogen Containing Heterocycles as Anticancer Agents: A Medicinal Chemistry Perspective
por: Kumar, Adarsh, et al.
Publicado: (2023)

Synthesis, and docking studies of novel heterocycles incorporating the indazolylthiazole moiety as antimicrobial and anticancer agents
por: Dawoud, Nadia T. A., et al.
Publicado: (2022)

Structure-Activity Relationships of Pentacyclic Triterpenoids as Potent and Selective Inhibitors against Human Carboxylesterase 1
por: Zou, Li-Wei, et al.
Publicado: (2017)

Supercritical Fluid Chromatography—Tandem Mass Spectrometry for Rapid Quantification of Pentacyclic Triterpenoids in Plant Extracts
por: Falev, Danil I., et al.
Publicado: (2022)

Parallel damage in mitochondrial and lysosomal compartments promotes efficient cell death with autophagy: The case of the pentacyclic triterpenoids
por: Martins, Waleska K., et al.
Publicado: (2015)

Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada Roots
por: Zergainoh, Nabila, et al.
Publicado: (2017)

Pharmacological Properties, Molecular Mechanisms, and Pharmaceutical Development of Asiatic Acid: A Pentacyclic Triterpenoid of Therapeutic Promise
por: Nagoor Meeran, Mohamed Fizur, et al.
Publicado: (2018)

Cell-Free Production of Pentacyclic Triterpenoid Compound Betulinic Acid from Betulin by the Engineered Saccharomyces cerevisiae
por: Wu, Jianan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_satkac0kfl1ec19g7a65b5823n