Cargando…

A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis

SIMPLE SUMMARY: According to the available data, colorectal cancer (CRC) is one of the most common malignant neoplasms. Depending on the location, type of cancer or gender, it is ranked 2nd to 4th in terms of incidence in the world. CRC, year by year, shows an increasing tendency in terms of both mo...

Descripción completa

Detalles Bibliográficos
Autores principales: Sawicki, Tomasz, Ruszkowska, Monika, Danielewicz, Anna, Niedźwiedzka, Ewa, Arłukowicz, Tomasz, Przybyłowicz, Katarzyna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122718/
https://www.ncbi.nlm.nih.gov/pubmed/33922197
http://dx.doi.org/10.3390/cancers13092025
_version_ 1783692694988521472
author Sawicki, Tomasz
Ruszkowska, Monika
Danielewicz, Anna
Niedźwiedzka, Ewa
Arłukowicz, Tomasz
Przybyłowicz, Katarzyna E.
author_facet Sawicki, Tomasz
Ruszkowska, Monika
Danielewicz, Anna
Niedźwiedzka, Ewa
Arłukowicz, Tomasz
Przybyłowicz, Katarzyna E.
author_sort Sawicki, Tomasz
collection PubMed
description SIMPLE SUMMARY: According to the available data, colorectal cancer (CRC) is one of the most common malignant neoplasms. Depending on the location, type of cancer or gender, it is ranked 2nd to 4th in terms of incidence in the world. CRC, year by year, shows an increasing tendency in terms of both morbidity and deaths. Many factors may be responsible for the development of this disease, including genetic and environmental factors. Considering all the aspects, we made efforts to systematize the available literature data in terms of epidemiology, risk factors, type and nature of symptoms, development stages, available and future diagnosis of colorectal cancer. ABSTRACT: This review article contains a concise consideration of genetic and environmental risk factors for colorectal cancer. Known risk factors associated with colorectal cancer include familial and hereditary factors and lifestyle-related and ecological factors. Lifestyle factors are significant because of the potential for improving our understanding of the disease. Physical inactivity, obesity, smoking and alcohol consumption can also be addressed through therapeutic interventions. We also made efforts to systematize available literature and data on epidemiology, diagnosis, type and nature of symptoms and disease stages. Further study of colorectal cancer and progress made globally is crucial to inform future strategies in controlling the disease’s burden through population-based preventative initiatives.
format Online
Article
Text
id pubmed-8122718
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-81227182021-05-16 A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis Sawicki, Tomasz Ruszkowska, Monika Danielewicz, Anna Niedźwiedzka, Ewa Arłukowicz, Tomasz Przybyłowicz, Katarzyna E. Cancers (Basel) Review SIMPLE SUMMARY: According to the available data, colorectal cancer (CRC) is one of the most common malignant neoplasms. Depending on the location, type of cancer or gender, it is ranked 2nd to 4th in terms of incidence in the world. CRC, year by year, shows an increasing tendency in terms of both morbidity and deaths. Many factors may be responsible for the development of this disease, including genetic and environmental factors. Considering all the aspects, we made efforts to systematize the available literature data in terms of epidemiology, risk factors, type and nature of symptoms, development stages, available and future diagnosis of colorectal cancer. ABSTRACT: This review article contains a concise consideration of genetic and environmental risk factors for colorectal cancer. Known risk factors associated with colorectal cancer include familial and hereditary factors and lifestyle-related and ecological factors. Lifestyle factors are significant because of the potential for improving our understanding of the disease. Physical inactivity, obesity, smoking and alcohol consumption can also be addressed through therapeutic interventions. We also made efforts to systematize available literature and data on epidemiology, diagnosis, type and nature of symptoms and disease stages. Further study of colorectal cancer and progress made globally is crucial to inform future strategies in controlling the disease’s burden through population-based preventative initiatives. MDPI 2021-04-22 /pmc/articles/PMC8122718/ /pubmed/33922197 http://dx.doi.org/10.3390/cancers13092025 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Sawicki, Tomasz
Ruszkowska, Monika
Danielewicz, Anna
Niedźwiedzka, Ewa
Arłukowicz, Tomasz
Przybyłowicz, Katarzyna E.
A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis
title A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis
title_full A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis
title_fullStr A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis
title_full_unstemmed A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis
title_short A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis
title_sort review of colorectal cancer in terms of epidemiology, risk factors, development, symptoms and diagnosis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122718/
https://www.ncbi.nlm.nih.gov/pubmed/33922197
http://dx.doi.org/10.3390/cancers13092025
work_keys_str_mv AT sawickitomasz areviewofcolorectalcancerintermsofepidemiologyriskfactorsdevelopmentsymptomsanddiagnosis
AT ruszkowskamonika areviewofcolorectalcancerintermsofepidemiologyriskfactorsdevelopmentsymptomsanddiagnosis
AT danielewiczanna areviewofcolorectalcancerintermsofepidemiologyriskfactorsdevelopmentsymptomsanddiagnosis
AT niedzwiedzkaewa areviewofcolorectalcancerintermsofepidemiologyriskfactorsdevelopmentsymptomsanddiagnosis
AT arłukowicztomasz areviewofcolorectalcancerintermsofepidemiologyriskfactorsdevelopmentsymptomsanddiagnosis
AT przybyłowiczkatarzynae areviewofcolorectalcancerintermsofepidemiologyriskfactorsdevelopmentsymptomsanddiagnosis
AT sawickitomasz reviewofcolorectalcancerintermsofepidemiologyriskfactorsdevelopmentsymptomsanddiagnosis
AT ruszkowskamonika reviewofcolorectalcancerintermsofepidemiologyriskfactorsdevelopmentsymptomsanddiagnosis
AT danielewiczanna reviewofcolorectalcancerintermsofepidemiologyriskfactorsdevelopmentsymptomsanddiagnosis
AT niedzwiedzkaewa reviewofcolorectalcancerintermsofepidemiologyriskfactorsdevelopmentsymptomsanddiagnosis
AT arłukowicztomasz reviewofcolorectalcancerintermsofepidemiologyriskfactorsdevelopmentsymptomsanddiagnosis
AT przybyłowiczkatarzynae reviewofcolorectalcancerintermsofepidemiologyriskfactorsdevelopmentsymptomsanddiagnosis