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Unlocking the Health Potential of Microalgae as Sustainable Sources of Bioactive Compounds
Microalgae are known to produce a plethora of compounds derived from the primary and secondary metabolism. Different studies have shown that these compounds may have allelopathic, antimicrobial, and antipredator activities. In addition, in vitro and in vivo screenings have shown that several compoun...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122763/ https://www.ncbi.nlm.nih.gov/pubmed/33922258 http://dx.doi.org/10.3390/ijms22094383 |
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author | Saide, Assunta Martínez, Kevin A. Ianora, Adrianna Lauritano, Chiara |
author_facet | Saide, Assunta Martínez, Kevin A. Ianora, Adrianna Lauritano, Chiara |
author_sort | Saide, Assunta |
collection | PubMed |
description | Microalgae are known to produce a plethora of compounds derived from the primary and secondary metabolism. Different studies have shown that these compounds may have allelopathic, antimicrobial, and antipredator activities. In addition, in vitro and in vivo screenings have shown that several compounds have interesting bioactivities (such as antioxidant, anti-inflammatory, anticancer, and antimicrobial) for the possible prevention and treatment of human pathologies. Additionally, the enzymatic pathways responsible for the synthesis of these compounds, and the targets and mechanisms of their action have also been investigated for a few species. However, further research is necessary for their full exploitation and possible pharmaceutical and other industrial applications. Here, we review the current knowledge on the chemical characteristics, biological activities, mechanism of action, and the enzymes involved in the synthesis of microalgal metabolites with potential benefits for human health. |
format | Online Article Text |
id | pubmed-8122763 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81227632021-05-16 Unlocking the Health Potential of Microalgae as Sustainable Sources of Bioactive Compounds Saide, Assunta Martínez, Kevin A. Ianora, Adrianna Lauritano, Chiara Int J Mol Sci Review Microalgae are known to produce a plethora of compounds derived from the primary and secondary metabolism. Different studies have shown that these compounds may have allelopathic, antimicrobial, and antipredator activities. In addition, in vitro and in vivo screenings have shown that several compounds have interesting bioactivities (such as antioxidant, anti-inflammatory, anticancer, and antimicrobial) for the possible prevention and treatment of human pathologies. Additionally, the enzymatic pathways responsible for the synthesis of these compounds, and the targets and mechanisms of their action have also been investigated for a few species. However, further research is necessary for their full exploitation and possible pharmaceutical and other industrial applications. Here, we review the current knowledge on the chemical characteristics, biological activities, mechanism of action, and the enzymes involved in the synthesis of microalgal metabolites with potential benefits for human health. MDPI 2021-04-22 /pmc/articles/PMC8122763/ /pubmed/33922258 http://dx.doi.org/10.3390/ijms22094383 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Saide, Assunta Martínez, Kevin A. Ianora, Adrianna Lauritano, Chiara Unlocking the Health Potential of Microalgae as Sustainable Sources of Bioactive Compounds |
title | Unlocking the Health Potential of Microalgae as Sustainable Sources of Bioactive Compounds |
title_full | Unlocking the Health Potential of Microalgae as Sustainable Sources of Bioactive Compounds |
title_fullStr | Unlocking the Health Potential of Microalgae as Sustainable Sources of Bioactive Compounds |
title_full_unstemmed | Unlocking the Health Potential of Microalgae as Sustainable Sources of Bioactive Compounds |
title_short | Unlocking the Health Potential of Microalgae as Sustainable Sources of Bioactive Compounds |
title_sort | unlocking the health potential of microalgae as sustainable sources of bioactive compounds |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122763/ https://www.ncbi.nlm.nih.gov/pubmed/33922258 http://dx.doi.org/10.3390/ijms22094383 |
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