Cargando…
Dissipation Behavior, Residue, and Risk Assessment of Benziothiazolinone in Apples
Benziothiazolinone is the first independently developed fungicide in China. It has been used to effectively control fungal diseases in a variety of fruits, vegetables, and crops. In this study, the degradation behavior and final residue of benziothiazolinone in apples is discussed, and the dietary r...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122877/ https://www.ncbi.nlm.nih.gov/pubmed/33922495 http://dx.doi.org/10.3390/ijerph18094478 |
_version_ | 1783692742000377856 |
---|---|
author | Chai, Yida Liu, Rong He, Wei Xu, Fuliu Chen, Zenglong Li, Li Li, Wei Yuan, Longfei |
author_facet | Chai, Yida Liu, Rong He, Wei Xu, Fuliu Chen, Zenglong Li, Li Li, Wei Yuan, Longfei |
author_sort | Chai, Yida |
collection | PubMed |
description | Benziothiazolinone is the first independently developed fungicide in China. It has been used to effectively control fungal diseases in a variety of fruits, vegetables, and crops. In this study, the degradation behavior and final residue of benziothiazolinone in apples is discussed, and the dietary risk to consumers was evaluated. High-performance liquid chromatography–tandem mass spectrometry (LC-MS/MS) was used to determine benziothiazolinone residues in apple samples from eight different regions of China. The average recovery of benziothiazolinone in apples was 85.5–100.2%, and the relative standard deviation (RSD) was 0.8–14.9%. The limits of the method of quantification of benziothiazolinone in apples was 0.01 mg/kg. Under good agricultural practices (GAP) conditions, the final residues of benziothiazolinone in apples were below 0.01 mg/kg, lower than the maximum residual limit (MRL) of China. Although the degradation half-lives of benziothiazolinone were 23.9 d–33.0 d, the risk quotient (RQ) of benziothiazolinone was 15.5% by calculating the national estimated daily intake and comparing it with the acceptable daily intake. These results suggested that under GAP conditions, the intake of benziothiazolinone from apples exhibits an acceptably low health risk on consumers. |
format | Online Article Text |
id | pubmed-8122877 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81228772021-05-16 Dissipation Behavior, Residue, and Risk Assessment of Benziothiazolinone in Apples Chai, Yida Liu, Rong He, Wei Xu, Fuliu Chen, Zenglong Li, Li Li, Wei Yuan, Longfei Int J Environ Res Public Health Article Benziothiazolinone is the first independently developed fungicide in China. It has been used to effectively control fungal diseases in a variety of fruits, vegetables, and crops. In this study, the degradation behavior and final residue of benziothiazolinone in apples is discussed, and the dietary risk to consumers was evaluated. High-performance liquid chromatography–tandem mass spectrometry (LC-MS/MS) was used to determine benziothiazolinone residues in apple samples from eight different regions of China. The average recovery of benziothiazolinone in apples was 85.5–100.2%, and the relative standard deviation (RSD) was 0.8–14.9%. The limits of the method of quantification of benziothiazolinone in apples was 0.01 mg/kg. Under good agricultural practices (GAP) conditions, the final residues of benziothiazolinone in apples were below 0.01 mg/kg, lower than the maximum residual limit (MRL) of China. Although the degradation half-lives of benziothiazolinone were 23.9 d–33.0 d, the risk quotient (RQ) of benziothiazolinone was 15.5% by calculating the national estimated daily intake and comparing it with the acceptable daily intake. These results suggested that under GAP conditions, the intake of benziothiazolinone from apples exhibits an acceptably low health risk on consumers. MDPI 2021-04-23 /pmc/articles/PMC8122877/ /pubmed/33922495 http://dx.doi.org/10.3390/ijerph18094478 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Chai, Yida Liu, Rong He, Wei Xu, Fuliu Chen, Zenglong Li, Li Li, Wei Yuan, Longfei Dissipation Behavior, Residue, and Risk Assessment of Benziothiazolinone in Apples |
title | Dissipation Behavior, Residue, and Risk Assessment of Benziothiazolinone in Apples |
title_full | Dissipation Behavior, Residue, and Risk Assessment of Benziothiazolinone in Apples |
title_fullStr | Dissipation Behavior, Residue, and Risk Assessment of Benziothiazolinone in Apples |
title_full_unstemmed | Dissipation Behavior, Residue, and Risk Assessment of Benziothiazolinone in Apples |
title_short | Dissipation Behavior, Residue, and Risk Assessment of Benziothiazolinone in Apples |
title_sort | dissipation behavior, residue, and risk assessment of benziothiazolinone in apples |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122877/ https://www.ncbi.nlm.nih.gov/pubmed/33922495 http://dx.doi.org/10.3390/ijerph18094478 |
work_keys_str_mv | AT chaiyida dissipationbehaviorresidueandriskassessmentofbenziothiazolinoneinapples AT liurong dissipationbehaviorresidueandriskassessmentofbenziothiazolinoneinapples AT hewei dissipationbehaviorresidueandriskassessmentofbenziothiazolinoneinapples AT xufuliu dissipationbehaviorresidueandriskassessmentofbenziothiazolinoneinapples AT chenzenglong dissipationbehaviorresidueandriskassessmentofbenziothiazolinoneinapples AT lili dissipationbehaviorresidueandriskassessmentofbenziothiazolinoneinapples AT liwei dissipationbehaviorresidueandriskassessmentofbenziothiazolinoneinapples AT yuanlongfei dissipationbehaviorresidueandriskassessmentofbenziothiazolinoneinapples |