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Dissipation Behavior, Residue, and Risk Assessment of Benziothiazolinone in Apples

Benziothiazolinone is the first independently developed fungicide in China. It has been used to effectively control fungal diseases in a variety of fruits, vegetables, and crops. In this study, the degradation behavior and final residue of benziothiazolinone in apples is discussed, and the dietary r...

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Autores principales: Chai, Yida, Liu, Rong, He, Wei, Xu, Fuliu, Chen, Zenglong, Li, Li, Li, Wei, Yuan, Longfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122877/
https://www.ncbi.nlm.nih.gov/pubmed/33922495
http://dx.doi.org/10.3390/ijerph18094478
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author Chai, Yida
Liu, Rong
He, Wei
Xu, Fuliu
Chen, Zenglong
Li, Li
Li, Wei
Yuan, Longfei
author_facet Chai, Yida
Liu, Rong
He, Wei
Xu, Fuliu
Chen, Zenglong
Li, Li
Li, Wei
Yuan, Longfei
author_sort Chai, Yida
collection PubMed
description Benziothiazolinone is the first independently developed fungicide in China. It has been used to effectively control fungal diseases in a variety of fruits, vegetables, and crops. In this study, the degradation behavior and final residue of benziothiazolinone in apples is discussed, and the dietary risk to consumers was evaluated. High-performance liquid chromatography–tandem mass spectrometry (LC-MS/MS) was used to determine benziothiazolinone residues in apple samples from eight different regions of China. The average recovery of benziothiazolinone in apples was 85.5–100.2%, and the relative standard deviation (RSD) was 0.8–14.9%. The limits of the method of quantification of benziothiazolinone in apples was 0.01 mg/kg. Under good agricultural practices (GAP) conditions, the final residues of benziothiazolinone in apples were below 0.01 mg/kg, lower than the maximum residual limit (MRL) of China. Although the degradation half-lives of benziothiazolinone were 23.9 d–33.0 d, the risk quotient (RQ) of benziothiazolinone was 15.5% by calculating the national estimated daily intake and comparing it with the acceptable daily intake. These results suggested that under GAP conditions, the intake of benziothiazolinone from apples exhibits an acceptably low health risk on consumers.
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spelling pubmed-81228772021-05-16 Dissipation Behavior, Residue, and Risk Assessment of Benziothiazolinone in Apples Chai, Yida Liu, Rong He, Wei Xu, Fuliu Chen, Zenglong Li, Li Li, Wei Yuan, Longfei Int J Environ Res Public Health Article Benziothiazolinone is the first independently developed fungicide in China. It has been used to effectively control fungal diseases in a variety of fruits, vegetables, and crops. In this study, the degradation behavior and final residue of benziothiazolinone in apples is discussed, and the dietary risk to consumers was evaluated. High-performance liquid chromatography–tandem mass spectrometry (LC-MS/MS) was used to determine benziothiazolinone residues in apple samples from eight different regions of China. The average recovery of benziothiazolinone in apples was 85.5–100.2%, and the relative standard deviation (RSD) was 0.8–14.9%. The limits of the method of quantification of benziothiazolinone in apples was 0.01 mg/kg. Under good agricultural practices (GAP) conditions, the final residues of benziothiazolinone in apples were below 0.01 mg/kg, lower than the maximum residual limit (MRL) of China. Although the degradation half-lives of benziothiazolinone were 23.9 d–33.0 d, the risk quotient (RQ) of benziothiazolinone was 15.5% by calculating the national estimated daily intake and comparing it with the acceptable daily intake. These results suggested that under GAP conditions, the intake of benziothiazolinone from apples exhibits an acceptably low health risk on consumers. MDPI 2021-04-23 /pmc/articles/PMC8122877/ /pubmed/33922495 http://dx.doi.org/10.3390/ijerph18094478 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chai, Yida
Liu, Rong
He, Wei
Xu, Fuliu
Chen, Zenglong
Li, Li
Li, Wei
Yuan, Longfei
Dissipation Behavior, Residue, and Risk Assessment of Benziothiazolinone in Apples
title Dissipation Behavior, Residue, and Risk Assessment of Benziothiazolinone in Apples
title_full Dissipation Behavior, Residue, and Risk Assessment of Benziothiazolinone in Apples
title_fullStr Dissipation Behavior, Residue, and Risk Assessment of Benziothiazolinone in Apples
title_full_unstemmed Dissipation Behavior, Residue, and Risk Assessment of Benziothiazolinone in Apples
title_short Dissipation Behavior, Residue, and Risk Assessment of Benziothiazolinone in Apples
title_sort dissipation behavior, residue, and risk assessment of benziothiazolinone in apples
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122877/
https://www.ncbi.nlm.nih.gov/pubmed/33922495
http://dx.doi.org/10.3390/ijerph18094478
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