ATPase Inhibitory Factor-1 Disrupts Mitochondrial Ca(2+) Handling and Promotes Pathological Cardiac Hypertrophy through CaMKIIδ

ATPase inhibitory factor-1 (IF1) preserves cellular ATP under conditions of respiratory collapse, yet the function of IF1 under normal respiring conditions is unresolved. We tested the hypothesis that IF1 promotes mitochondrial dysfunction and pathological cardiomyocyte hypertrophy in the context of...

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Detalles Bibliográficos
Autores principales: Pavez-Giani, Mario G., Sánchez-Aguilera, Pablo I., Bomer, Nils, Miyamoto, Shigeki, Booij, Harmen G., Giraldo, Paula, Oberdorf-Maass, Silke U., Nijholt, Kirsten T., Yurista, Salva R., Milting, Hendrik, van der Meer, Peter, de Boer, Rudolf A., Heller Brown, Joan, Sillje, Herman W. H., Westenbrink, B. Daan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122940/
https://www.ncbi.nlm.nih.gov/pubmed/33922643
http://dx.doi.org/10.3390/ijms22094427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122940/
https://www.ncbi.nlm.nih.gov/pubmed/33922643
http://dx.doi.org/10.3390/ijms22094427

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