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Development of a Robust High-Throughput Screening Platform for Inhibitors of the Striatal-Enriched Tyrosine Phosphatase (STEP)

Many human diseases are the result of abnormal expression or activation of protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs). Not surprisingly, more than 30 tyrosine kinase inhibitors (TKIs) are currently in clinical use and provide unique treatment options for many patients....

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Detalles Bibliográficos
Autores principales: Lambert, Lester J, Grotegut, Stefan, Celeridad, Maria, Gosalia, Palak, Backer, Laurent JS De, Bobkov, Andrey A, Salaniwal, Sumeet, Chung, Thomas DY, Zeng, Fu-Yue, Pass, Ian, Lombroso, Paul J, Cosford, Nicholas DP, Tautz, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122956/
https://www.ncbi.nlm.nih.gov/pubmed/33922601
http://dx.doi.org/10.3390/ijms22094417