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Development of a Robust High-Throughput Screening Platform for Inhibitors of the Striatal-Enriched Tyrosine Phosphatase (STEP)
Many human diseases are the result of abnormal expression or activation of protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs). Not surprisingly, more than 30 tyrosine kinase inhibitors (TKIs) are currently in clinical use and provide unique treatment options for many patients....
Autores principales: | Lambert, Lester J, Grotegut, Stefan, Celeridad, Maria, Gosalia, Palak, Backer, Laurent JS De, Bobkov, Andrey A, Salaniwal, Sumeet, Chung, Thomas DY, Zeng, Fu-Yue, Pass, Ian, Lombroso, Paul J, Cosford, Nicholas DP, Tautz, Lutz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122956/ https://www.ncbi.nlm.nih.gov/pubmed/33922601 http://dx.doi.org/10.3390/ijms22094417 |
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