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A Role for TGFβ Signaling in Preclinical Osteolytic Estrogen Receptor-Positive Breast Cancer Bone Metastases Progression

While tumoral Smad-mediated transforming growth factor β (TGFβ) signaling drives osteolytic estrogen receptor α-negative (ER-) breast cancer bone metastases (BMETs) in preclinical models, its role in ER+ BMETs, representing the majority of clinical BMETs, has not been documented. Experiments were un...

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Detalles Bibliográficos
Autores principales:	Cheng, Julia N., Frye, Jennifer B., Whitman, Susan A., Kunihiro, Andrew G., Pandey, Ritu, Funk, Janet L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123146/ https://www.ncbi.nlm.nih.gov/pubmed/33923316 http://dx.doi.org/10.3390/ijms22094463

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