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Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses

Hyaluronic acid (HA) is a glycosaminoglycan that was first isolated and identified from the vitreous body of a bull’s eye. HA is ubiquitous in the soft connective tissues of animals and therefore has high tissue compatibility for use in medication. Because of HA’s biological safety and water retenti...

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Autores principales: Chang, Wan-Hsin, Liu, Pei-Yi, Lin, Min-Hsuan, Lu, Chien-Ju, Chou, Hsuan-Yi, Nian, Chih-Yu, Jiang, Yuan-Ting, Hsu, Yuan-Hao Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123179/
https://www.ncbi.nlm.nih.gov/pubmed/33923222
http://dx.doi.org/10.3390/molecules26092485
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author Chang, Wan-Hsin
Liu, Pei-Yi
Lin, Min-Hsuan
Lu, Chien-Ju
Chou, Hsuan-Yi
Nian, Chih-Yu
Jiang, Yuan-Ting
Hsu, Yuan-Hao Howard
author_facet Chang, Wan-Hsin
Liu, Pei-Yi
Lin, Min-Hsuan
Lu, Chien-Ju
Chou, Hsuan-Yi
Nian, Chih-Yu
Jiang, Yuan-Ting
Hsu, Yuan-Hao Howard
author_sort Chang, Wan-Hsin
collection PubMed
description Hyaluronic acid (HA) is a glycosaminoglycan that was first isolated and identified from the vitreous body of a bull’s eye. HA is ubiquitous in the soft connective tissues of animals and therefore has high tissue compatibility for use in medication. Because of HA’s biological safety and water retention properties, it has many ophthalmology-related applications, such as in intravitreal injection, dry eye treatment, and contact lenses. Due to its broad range of applications, the identification and quantification of HA is a critical topic. This review article discusses current methods for analyzing HA. Contact lenses have become a widely used medical device, with HA commonly used as an additive to their production material, surface coating, and multipurpose solution. HA molecules on contact lenses retain moisture and increase the wearer’s comfort. HA absorbed by contact lenses can also gradually release to the anterior segment of the eyes to treat dry eye. This review discusses applications of HA in ophthalmology.
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spelling pubmed-81231792021-05-16 Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses Chang, Wan-Hsin Liu, Pei-Yi Lin, Min-Hsuan Lu, Chien-Ju Chou, Hsuan-Yi Nian, Chih-Yu Jiang, Yuan-Ting Hsu, Yuan-Hao Howard Molecules Review Hyaluronic acid (HA) is a glycosaminoglycan that was first isolated and identified from the vitreous body of a bull’s eye. HA is ubiquitous in the soft connective tissues of animals and therefore has high tissue compatibility for use in medication. Because of HA’s biological safety and water retention properties, it has many ophthalmology-related applications, such as in intravitreal injection, dry eye treatment, and contact lenses. Due to its broad range of applications, the identification and quantification of HA is a critical topic. This review article discusses current methods for analyzing HA. Contact lenses have become a widely used medical device, with HA commonly used as an additive to their production material, surface coating, and multipurpose solution. HA molecules on contact lenses retain moisture and increase the wearer’s comfort. HA absorbed by contact lenses can also gradually release to the anterior segment of the eyes to treat dry eye. This review discusses applications of HA in ophthalmology. MDPI 2021-04-24 /pmc/articles/PMC8123179/ /pubmed/33923222 http://dx.doi.org/10.3390/molecules26092485 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Chang, Wan-Hsin
Liu, Pei-Yi
Lin, Min-Hsuan
Lu, Chien-Ju
Chou, Hsuan-Yi
Nian, Chih-Yu
Jiang, Yuan-Ting
Hsu, Yuan-Hao Howard
Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses
title Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses
title_full Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses
title_fullStr Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses
title_full_unstemmed Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses
title_short Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses
title_sort applications of hyaluronic acid in ophthalmology and contact lenses
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123179/
https://www.ncbi.nlm.nih.gov/pubmed/33923222
http://dx.doi.org/10.3390/molecules26092485
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