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Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses
Hyaluronic acid (HA) is a glycosaminoglycan that was first isolated and identified from the vitreous body of a bull’s eye. HA is ubiquitous in the soft connective tissues of animals and therefore has high tissue compatibility for use in medication. Because of HA’s biological safety and water retenti...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123179/ https://www.ncbi.nlm.nih.gov/pubmed/33923222 http://dx.doi.org/10.3390/molecules26092485 |
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author | Chang, Wan-Hsin Liu, Pei-Yi Lin, Min-Hsuan Lu, Chien-Ju Chou, Hsuan-Yi Nian, Chih-Yu Jiang, Yuan-Ting Hsu, Yuan-Hao Howard |
author_facet | Chang, Wan-Hsin Liu, Pei-Yi Lin, Min-Hsuan Lu, Chien-Ju Chou, Hsuan-Yi Nian, Chih-Yu Jiang, Yuan-Ting Hsu, Yuan-Hao Howard |
author_sort | Chang, Wan-Hsin |
collection | PubMed |
description | Hyaluronic acid (HA) is a glycosaminoglycan that was first isolated and identified from the vitreous body of a bull’s eye. HA is ubiquitous in the soft connective tissues of animals and therefore has high tissue compatibility for use in medication. Because of HA’s biological safety and water retention properties, it has many ophthalmology-related applications, such as in intravitreal injection, dry eye treatment, and contact lenses. Due to its broad range of applications, the identification and quantification of HA is a critical topic. This review article discusses current methods for analyzing HA. Contact lenses have become a widely used medical device, with HA commonly used as an additive to their production material, surface coating, and multipurpose solution. HA molecules on contact lenses retain moisture and increase the wearer’s comfort. HA absorbed by contact lenses can also gradually release to the anterior segment of the eyes to treat dry eye. This review discusses applications of HA in ophthalmology. |
format | Online Article Text |
id | pubmed-8123179 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81231792021-05-16 Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses Chang, Wan-Hsin Liu, Pei-Yi Lin, Min-Hsuan Lu, Chien-Ju Chou, Hsuan-Yi Nian, Chih-Yu Jiang, Yuan-Ting Hsu, Yuan-Hao Howard Molecules Review Hyaluronic acid (HA) is a glycosaminoglycan that was first isolated and identified from the vitreous body of a bull’s eye. HA is ubiquitous in the soft connective tissues of animals and therefore has high tissue compatibility for use in medication. Because of HA’s biological safety and water retention properties, it has many ophthalmology-related applications, such as in intravitreal injection, dry eye treatment, and contact lenses. Due to its broad range of applications, the identification and quantification of HA is a critical topic. This review article discusses current methods for analyzing HA. Contact lenses have become a widely used medical device, with HA commonly used as an additive to their production material, surface coating, and multipurpose solution. HA molecules on contact lenses retain moisture and increase the wearer’s comfort. HA absorbed by contact lenses can also gradually release to the anterior segment of the eyes to treat dry eye. This review discusses applications of HA in ophthalmology. MDPI 2021-04-24 /pmc/articles/PMC8123179/ /pubmed/33923222 http://dx.doi.org/10.3390/molecules26092485 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Chang, Wan-Hsin Liu, Pei-Yi Lin, Min-Hsuan Lu, Chien-Ju Chou, Hsuan-Yi Nian, Chih-Yu Jiang, Yuan-Ting Hsu, Yuan-Hao Howard Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses |
title | Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses |
title_full | Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses |
title_fullStr | Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses |
title_full_unstemmed | Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses |
title_short | Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses |
title_sort | applications of hyaluronic acid in ophthalmology and contact lenses |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123179/ https://www.ncbi.nlm.nih.gov/pubmed/33923222 http://dx.doi.org/10.3390/molecules26092485 |
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