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SARS-CoV-2 Seroprevalence in Healthcare Workers in Germany: A Follow-Up Study

SARS-CoV-2 is a worldwide challenge for the medical sector. Healthcare workers (HCW) are a cohort vulnerable to SARS-CoV-2 infection due to frequent and close contact with COVID-19 patients. However, they are also well trained and equipped with protective gear. The SARS-CoV-2 IgG antibody status was...

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Autores principales: Korth, Johannes, Wilde, Benjamin, Dolff, Sebastian, Frisch, Jasmin, Jahn, Michael, Krawczyk, Adalbert, Trilling, Mirko, Schipper, Leonie, Cordes, Sebastian, Ross, Birgit, Lindemann, Monika, Kribben, Andreas, Dittmer, Ulf, Witzke, Oliver, Herrmann, Anke, Anastasiou, Olympia Evdoxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123190/
https://www.ncbi.nlm.nih.gov/pubmed/33922895
http://dx.doi.org/10.3390/ijerph18094540
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author Korth, Johannes
Wilde, Benjamin
Dolff, Sebastian
Frisch, Jasmin
Jahn, Michael
Krawczyk, Adalbert
Trilling, Mirko
Schipper, Leonie
Cordes, Sebastian
Ross, Birgit
Lindemann, Monika
Kribben, Andreas
Dittmer, Ulf
Witzke, Oliver
Herrmann, Anke
Anastasiou, Olympia Evdoxia
author_facet Korth, Johannes
Wilde, Benjamin
Dolff, Sebastian
Frisch, Jasmin
Jahn, Michael
Krawczyk, Adalbert
Trilling, Mirko
Schipper, Leonie
Cordes, Sebastian
Ross, Birgit
Lindemann, Monika
Kribben, Andreas
Dittmer, Ulf
Witzke, Oliver
Herrmann, Anke
Anastasiou, Olympia Evdoxia
author_sort Korth, Johannes
collection PubMed
description SARS-CoV-2 is a worldwide challenge for the medical sector. Healthcare workers (HCW) are a cohort vulnerable to SARS-CoV-2 infection due to frequent and close contact with COVID-19 patients. However, they are also well trained and equipped with protective gear. The SARS-CoV-2 IgG antibody status was assessed at three different time points in 450 HCW of the University Hospital Essen in Germany. HCW were stratified according to contact frequencies with COVID-19 patients in (I) a high-risk group with daily contacts with known COVID-19 patients (n = 338), (II) an intermediate-risk group with daily contacts with non-COVID-19 patients (n = 78), and (III) a low-risk group without patient contacts (n = 34). The overall seroprevalence increased from 2.2% in March–May to 4.0% in June–July to 5.1% in October–December. The SARS-CoV-2 IgG detection rate was not significantly different between the high-risk group (1.8%; 3.8%; 5.5%), the intermediate-risk group (5.1%; 6.3%; 6.1%), and the low-risk group (0%, 0%, 0%). The overall SARS-CoV-2 seroprevalence remained low in HCW in western Germany one year after the outbreak of COVID-19 in Germany, and hygiene standards seemed to be effective in preventing patient-to-staff virus transmission.
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spelling pubmed-81231902021-05-16 SARS-CoV-2 Seroprevalence in Healthcare Workers in Germany: A Follow-Up Study Korth, Johannes Wilde, Benjamin Dolff, Sebastian Frisch, Jasmin Jahn, Michael Krawczyk, Adalbert Trilling, Mirko Schipper, Leonie Cordes, Sebastian Ross, Birgit Lindemann, Monika Kribben, Andreas Dittmer, Ulf Witzke, Oliver Herrmann, Anke Anastasiou, Olympia Evdoxia Int J Environ Res Public Health Article SARS-CoV-2 is a worldwide challenge for the medical sector. Healthcare workers (HCW) are a cohort vulnerable to SARS-CoV-2 infection due to frequent and close contact with COVID-19 patients. However, they are also well trained and equipped with protective gear. The SARS-CoV-2 IgG antibody status was assessed at three different time points in 450 HCW of the University Hospital Essen in Germany. HCW were stratified according to contact frequencies with COVID-19 patients in (I) a high-risk group with daily contacts with known COVID-19 patients (n = 338), (II) an intermediate-risk group with daily contacts with non-COVID-19 patients (n = 78), and (III) a low-risk group without patient contacts (n = 34). The overall seroprevalence increased from 2.2% in March–May to 4.0% in June–July to 5.1% in October–December. The SARS-CoV-2 IgG detection rate was not significantly different between the high-risk group (1.8%; 3.8%; 5.5%), the intermediate-risk group (5.1%; 6.3%; 6.1%), and the low-risk group (0%, 0%, 0%). The overall SARS-CoV-2 seroprevalence remained low in HCW in western Germany one year after the outbreak of COVID-19 in Germany, and hygiene standards seemed to be effective in preventing patient-to-staff virus transmission. MDPI 2021-04-25 /pmc/articles/PMC8123190/ /pubmed/33922895 http://dx.doi.org/10.3390/ijerph18094540 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Korth, Johannes
Wilde, Benjamin
Dolff, Sebastian
Frisch, Jasmin
Jahn, Michael
Krawczyk, Adalbert
Trilling, Mirko
Schipper, Leonie
Cordes, Sebastian
Ross, Birgit
Lindemann, Monika
Kribben, Andreas
Dittmer, Ulf
Witzke, Oliver
Herrmann, Anke
Anastasiou, Olympia Evdoxia
SARS-CoV-2 Seroprevalence in Healthcare Workers in Germany: A Follow-Up Study
title SARS-CoV-2 Seroprevalence in Healthcare Workers in Germany: A Follow-Up Study
title_full SARS-CoV-2 Seroprevalence in Healthcare Workers in Germany: A Follow-Up Study
title_fullStr SARS-CoV-2 Seroprevalence in Healthcare Workers in Germany: A Follow-Up Study
title_full_unstemmed SARS-CoV-2 Seroprevalence in Healthcare Workers in Germany: A Follow-Up Study
title_short SARS-CoV-2 Seroprevalence in Healthcare Workers in Germany: A Follow-Up Study
title_sort sars-cov-2 seroprevalence in healthcare workers in germany: a follow-up study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123190/
https://www.ncbi.nlm.nih.gov/pubmed/33922895
http://dx.doi.org/10.3390/ijerph18094540
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