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Candida auris: A Quick Review on Identification, Current Treatments, and Challenges

Candida auris is a novel and major fungal pathogen that has triggered several outbreaks in the last decade. The few drugs available to treat fungal diseases, the fact that this yeast has a high rate of multidrug resistance and the occurrence of misleading identifications, and the ability of forming...

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Autores principales: Černáková, Lucia, Roudbary, Maryam, Brás, Susana, Tafaj, Silva, Rodrigues, Célia F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123192/
https://www.ncbi.nlm.nih.gov/pubmed/33922907
http://dx.doi.org/10.3390/ijms22094470
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author Černáková, Lucia
Roudbary, Maryam
Brás, Susana
Tafaj, Silva
Rodrigues, Célia F.
author_facet Černáková, Lucia
Roudbary, Maryam
Brás, Susana
Tafaj, Silva
Rodrigues, Célia F.
author_sort Černáková, Lucia
collection PubMed
description Candida auris is a novel and major fungal pathogen that has triggered several outbreaks in the last decade. The few drugs available to treat fungal diseases, the fact that this yeast has a high rate of multidrug resistance and the occurrence of misleading identifications, and the ability of forming biofilms (naturally more resistant to drugs) has made treatments of C. auris infections highly difficult. This review intends to quickly illustrate the main issues in C. auris identification, available treatments and the associated mechanisms of resistance, and the novel and alternative treatment and drugs (natural and synthetic) that have been recently reported.
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spelling pubmed-81231922021-05-16 Candida auris: A Quick Review on Identification, Current Treatments, and Challenges Černáková, Lucia Roudbary, Maryam Brás, Susana Tafaj, Silva Rodrigues, Célia F. Int J Mol Sci Review Candida auris is a novel and major fungal pathogen that has triggered several outbreaks in the last decade. The few drugs available to treat fungal diseases, the fact that this yeast has a high rate of multidrug resistance and the occurrence of misleading identifications, and the ability of forming biofilms (naturally more resistant to drugs) has made treatments of C. auris infections highly difficult. This review intends to quickly illustrate the main issues in C. auris identification, available treatments and the associated mechanisms of resistance, and the novel and alternative treatment and drugs (natural and synthetic) that have been recently reported. MDPI 2021-04-25 /pmc/articles/PMC8123192/ /pubmed/33922907 http://dx.doi.org/10.3390/ijms22094470 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Černáková, Lucia
Roudbary, Maryam
Brás, Susana
Tafaj, Silva
Rodrigues, Célia F.
Candida auris: A Quick Review on Identification, Current Treatments, and Challenges
title Candida auris: A Quick Review on Identification, Current Treatments, and Challenges
title_full Candida auris: A Quick Review on Identification, Current Treatments, and Challenges
title_fullStr Candida auris: A Quick Review on Identification, Current Treatments, and Challenges
title_full_unstemmed Candida auris: A Quick Review on Identification, Current Treatments, and Challenges
title_short Candida auris: A Quick Review on Identification, Current Treatments, and Challenges
title_sort candida auris: a quick review on identification, current treatments, and challenges
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123192/
https://www.ncbi.nlm.nih.gov/pubmed/33922907
http://dx.doi.org/10.3390/ijms22094470
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