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Candida auris: A Quick Review on Identification, Current Treatments, and Challenges
Candida auris is a novel and major fungal pathogen that has triggered several outbreaks in the last decade. The few drugs available to treat fungal diseases, the fact that this yeast has a high rate of multidrug resistance and the occurrence of misleading identifications, and the ability of forming...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123192/ https://www.ncbi.nlm.nih.gov/pubmed/33922907 http://dx.doi.org/10.3390/ijms22094470 |
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author | Černáková, Lucia Roudbary, Maryam Brás, Susana Tafaj, Silva Rodrigues, Célia F. |
author_facet | Černáková, Lucia Roudbary, Maryam Brás, Susana Tafaj, Silva Rodrigues, Célia F. |
author_sort | Černáková, Lucia |
collection | PubMed |
description | Candida auris is a novel and major fungal pathogen that has triggered several outbreaks in the last decade. The few drugs available to treat fungal diseases, the fact that this yeast has a high rate of multidrug resistance and the occurrence of misleading identifications, and the ability of forming biofilms (naturally more resistant to drugs) has made treatments of C. auris infections highly difficult. This review intends to quickly illustrate the main issues in C. auris identification, available treatments and the associated mechanisms of resistance, and the novel and alternative treatment and drugs (natural and synthetic) that have been recently reported. |
format | Online Article Text |
id | pubmed-8123192 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81231922021-05-16 Candida auris: A Quick Review on Identification, Current Treatments, and Challenges Černáková, Lucia Roudbary, Maryam Brás, Susana Tafaj, Silva Rodrigues, Célia F. Int J Mol Sci Review Candida auris is a novel and major fungal pathogen that has triggered several outbreaks in the last decade. The few drugs available to treat fungal diseases, the fact that this yeast has a high rate of multidrug resistance and the occurrence of misleading identifications, and the ability of forming biofilms (naturally more resistant to drugs) has made treatments of C. auris infections highly difficult. This review intends to quickly illustrate the main issues in C. auris identification, available treatments and the associated mechanisms of resistance, and the novel and alternative treatment and drugs (natural and synthetic) that have been recently reported. MDPI 2021-04-25 /pmc/articles/PMC8123192/ /pubmed/33922907 http://dx.doi.org/10.3390/ijms22094470 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Černáková, Lucia Roudbary, Maryam Brás, Susana Tafaj, Silva Rodrigues, Célia F. Candida auris: A Quick Review on Identification, Current Treatments, and Challenges |
title | Candida auris: A Quick Review on Identification, Current Treatments, and Challenges |
title_full | Candida auris: A Quick Review on Identification, Current Treatments, and Challenges |
title_fullStr | Candida auris: A Quick Review on Identification, Current Treatments, and Challenges |
title_full_unstemmed | Candida auris: A Quick Review on Identification, Current Treatments, and Challenges |
title_short | Candida auris: A Quick Review on Identification, Current Treatments, and Challenges |
title_sort | candida auris: a quick review on identification, current treatments, and challenges |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123192/ https://www.ncbi.nlm.nih.gov/pubmed/33922907 http://dx.doi.org/10.3390/ijms22094470 |
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