The Role of Resveratrol in Human Male Fertility

Resveratrol (RSV) (3,4′,5 trihydroxystilbene) is a natural non-flavonoid polyphenol widely present in the Mediterranean diet. In particular, RSV is found in grapes, peanuts, berries, and red wine. Many beneficial effects of this molecule on human health have been reported. In fact, it improves some...

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Autores principales: Mongioì, Laura M., Perelli, Sarah, Condorelli, Rosita A., Barbagallo, Federica, Crafa, Andrea, Cannarella, Rossella, La Vignera, Sandro, Calogero, Aldo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123193/
https://www.ncbi.nlm.nih.gov/pubmed/33923359
http://dx.doi.org/10.3390/molecules26092495
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author Mongioì, Laura M.
Perelli, Sarah
Condorelli, Rosita A.
Barbagallo, Federica
Crafa, Andrea
Cannarella, Rossella
La Vignera, Sandro
Calogero, Aldo E.
author_facet Mongioì, Laura M.
Perelli, Sarah
Condorelli, Rosita A.
Barbagallo, Federica
Crafa, Andrea
Cannarella, Rossella
La Vignera, Sandro
Calogero, Aldo E.
author_sort Mongioì, Laura M.
collection PubMed
description Resveratrol (RSV) (3,4′,5 trihydroxystilbene) is a natural non-flavonoid polyphenol widely present in the Mediterranean diet. In particular, RSV is found in grapes, peanuts, berries, and red wine. Many beneficial effects of this molecule on human health have been reported. In fact, it improves some clinical aspects of various diseases, such as obesity, tumors, hypertension, Alzheimer’s disease, stroke, cardiovascular diseases, and diabetes mellitus. However, little is known about the relationship between this compound and male fertility and the few available results are often controversial. Therefore, this review evaluated the effects of RSV on human male fertility and the mechanisms through which this polyphenol could act on human spermatozoa.
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spelling pubmed-81231932021-05-16 The Role of Resveratrol in Human Male Fertility Mongioì, Laura M. Perelli, Sarah Condorelli, Rosita A. Barbagallo, Federica Crafa, Andrea Cannarella, Rossella La Vignera, Sandro Calogero, Aldo E. Molecules Review Resveratrol (RSV) (3,4′,5 trihydroxystilbene) is a natural non-flavonoid polyphenol widely present in the Mediterranean diet. In particular, RSV is found in grapes, peanuts, berries, and red wine. Many beneficial effects of this molecule on human health have been reported. In fact, it improves some clinical aspects of various diseases, such as obesity, tumors, hypertension, Alzheimer’s disease, stroke, cardiovascular diseases, and diabetes mellitus. However, little is known about the relationship between this compound and male fertility and the few available results are often controversial. Therefore, this review evaluated the effects of RSV on human male fertility and the mechanisms through which this polyphenol could act on human spermatozoa. MDPI 2021-04-24 /pmc/articles/PMC8123193/ /pubmed/33923359 http://dx.doi.org/10.3390/molecules26092495 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mongioì, Laura M.
Perelli, Sarah
Condorelli, Rosita A.
Barbagallo, Federica
Crafa, Andrea
Cannarella, Rossella
La Vignera, Sandro
Calogero, Aldo E.
The Role of Resveratrol in Human Male Fertility
title The Role of Resveratrol in Human Male Fertility
title_full The Role of Resveratrol in Human Male Fertility
title_fullStr The Role of Resveratrol in Human Male Fertility
title_full_unstemmed The Role of Resveratrol in Human Male Fertility
title_short The Role of Resveratrol in Human Male Fertility
title_sort role of resveratrol in human male fertility
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123193/
https://www.ncbi.nlm.nih.gov/pubmed/33923359
http://dx.doi.org/10.3390/molecules26092495
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