Clear-cell variant of oral squamous cell carcinoma: A rare entity

Clear-cell variant of oral squamous cell carcinoma is an extremely rare entity in the maxillofacial region. We report a case of 42-year-old female who presented with a soft-tissue growth with erythematous and nonscrapable irregular white patches on the left alveolar mucosa for the past 3 months. His...

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Autores principales: Ramani, Pratibha, Gheena, S, Karunagaran, Monika, Hannah, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123239/
https://www.ncbi.nlm.nih.gov/pubmed/34083965
http://dx.doi.org/10.4103/jomfp.JOMFP_295_20
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author Ramani, Pratibha
Gheena, S
Karunagaran, Monika
Hannah, R
author_facet Ramani, Pratibha
Gheena, S
Karunagaran, Monika
Hannah, R
author_sort Ramani, Pratibha
collection PubMed
description Clear-cell variant of oral squamous cell carcinoma is an extremely rare entity in the maxillofacial region. We report a case of 42-year-old female who presented with a soft-tissue growth with erythematous and nonscrapable irregular white patches on the left alveolar mucosa for the past 3 months. Histopathologic examination showed lobules and sheets of clear cells with features of malignancy extending from the surface epithelium. Periodic acid–Schiff and mucicarmine stains showed a negative reaction. Immunohistochemical study using antibody for pan-cytokeratin revealed intense positivity and negative for the markers such as S-100, smooth muscle actin and CD 117.
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spelling pubmed-81232392021-06-02 Clear-cell variant of oral squamous cell carcinoma: A rare entity Ramani, Pratibha Gheena, S Karunagaran, Monika Hannah, R J Oral Maxillofac Pathol Case Report Clear-cell variant of oral squamous cell carcinoma is an extremely rare entity in the maxillofacial region. We report a case of 42-year-old female who presented with a soft-tissue growth with erythematous and nonscrapable irregular white patches on the left alveolar mucosa for the past 3 months. Histopathologic examination showed lobules and sheets of clear cells with features of malignancy extending from the surface epithelium. Periodic acid–Schiff and mucicarmine stains showed a negative reaction. Immunohistochemical study using antibody for pan-cytokeratin revealed intense positivity and negative for the markers such as S-100, smooth muscle actin and CD 117. Wolters Kluwer - Medknow 2021-03 2021-03-19 /pmc/articles/PMC8123239/ /pubmed/34083965 http://dx.doi.org/10.4103/jomfp.JOMFP_295_20 Text en Copyright: © 2021 Journal of Oral and Maxillofacial Pathology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Ramani, Pratibha
Gheena, S
Karunagaran, Monika
Hannah, R
Clear-cell variant of oral squamous cell carcinoma: A rare entity
title Clear-cell variant of oral squamous cell carcinoma: A rare entity
title_full Clear-cell variant of oral squamous cell carcinoma: A rare entity
title_fullStr Clear-cell variant of oral squamous cell carcinoma: A rare entity
title_full_unstemmed Clear-cell variant of oral squamous cell carcinoma: A rare entity
title_short Clear-cell variant of oral squamous cell carcinoma: A rare entity
title_sort clear-cell variant of oral squamous cell carcinoma: a rare entity
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123239/
https://www.ncbi.nlm.nih.gov/pubmed/34083965
http://dx.doi.org/10.4103/jomfp.JOMFP_295_20
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AT hannahr clearcellvariantoforalsquamouscellcarcinomaarareentity

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