Orthokeratinized odontogenic cyst: Report of eight cases and review of literature regarding its malignant transformation

Orthokeratinized odontogenic cyst (OOC) is an uncommon odontogenic cyst. It has been categorized as a subtype of odontogenic keratocyst (OKC). In 2005, it was classified as a distinct entity. OOC should be histopathologically differentiated from OKC, which has a higher recurrence rate and lower mali...

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Autores principales: Mahdavi, Nazanin, Zavarei, Mona, Derakhshan, Samira, Nasab, Mahboube Hashemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123257/
https://www.ncbi.nlm.nih.gov/pubmed/34083963
http://dx.doi.org/10.4103/jomfp.JOMFP_1_20
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author Mahdavi, Nazanin
Zavarei, Mona
Derakhshan, Samira
Nasab, Mahboube Hashemi
author_facet Mahdavi, Nazanin
Zavarei, Mona
Derakhshan, Samira
Nasab, Mahboube Hashemi
author_sort Mahdavi, Nazanin
collection PubMed
description Orthokeratinized odontogenic cyst (OOC) is an uncommon odontogenic cyst. It has been categorized as a subtype of odontogenic keratocyst (OKC). In 2005, it was classified as a distinct entity. OOC should be histopathologically differentiated from OKC, which has a higher recurrence rate and lower malignant potential. In addition, OOC should be examined for malignant transformation. The epithelium of odontogenic cysts may rarely show malignant transformation. However, malignant transformation has been reported in inflammatory cysts such as the residual cyst and periapical cyst. The number of carcinomas arising from an OOC is low. This paper describes eight cases of OOC; out of which, two showed the development of squamous cell carcinoma from their epithelial lining.
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spelling pubmed-81232572021-06-02 Orthokeratinized odontogenic cyst: Report of eight cases and review of literature regarding its malignant transformation Mahdavi, Nazanin Zavarei, Mona Derakhshan, Samira Nasab, Mahboube Hashemi J Oral Maxillofac Pathol Case Report Orthokeratinized odontogenic cyst (OOC) is an uncommon odontogenic cyst. It has been categorized as a subtype of odontogenic keratocyst (OKC). In 2005, it was classified as a distinct entity. OOC should be histopathologically differentiated from OKC, which has a higher recurrence rate and lower malignant potential. In addition, OOC should be examined for malignant transformation. The epithelium of odontogenic cysts may rarely show malignant transformation. However, malignant transformation has been reported in inflammatory cysts such as the residual cyst and periapical cyst. The number of carcinomas arising from an OOC is low. This paper describes eight cases of OOC; out of which, two showed the development of squamous cell carcinoma from their epithelial lining. Wolters Kluwer - Medknow 2021-03 2021-03-19 /pmc/articles/PMC8123257/ /pubmed/34083963 http://dx.doi.org/10.4103/jomfp.JOMFP_1_20 Text en Copyright: © 2021 Journal of Oral and Maxillofacial Pathology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Mahdavi, Nazanin
Zavarei, Mona
Derakhshan, Samira
Nasab, Mahboube Hashemi
Orthokeratinized odontogenic cyst: Report of eight cases and review of literature regarding its malignant transformation
title Orthokeratinized odontogenic cyst: Report of eight cases and review of literature regarding its malignant transformation
title_full Orthokeratinized odontogenic cyst: Report of eight cases and review of literature regarding its malignant transformation
title_fullStr Orthokeratinized odontogenic cyst: Report of eight cases and review of literature regarding its malignant transformation
title_full_unstemmed Orthokeratinized odontogenic cyst: Report of eight cases and review of literature regarding its malignant transformation
title_short Orthokeratinized odontogenic cyst: Report of eight cases and review of literature regarding its malignant transformation
title_sort orthokeratinized odontogenic cyst: report of eight cases and review of literature regarding its malignant transformation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123257/
https://www.ncbi.nlm.nih.gov/pubmed/34083963
http://dx.doi.org/10.4103/jomfp.JOMFP_1_20
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