Cargando…

Aggregation and Its Influence on the Bioactivities of a Novel Antimicrobial Peptide, Temporin-PF, and Its Analogues

Temporin is an antimicrobial peptide (AMP) family discovered in the skin secretion of ranid frog that has become a promising alternative for conventional antibiotic therapy. Herein, a novel temporin peptide, Temporin-PF (TPF), was successfully identified from Pelophylax fukienensis. It exhibited pot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zai, Yu, Xi, Xinping, Ye, Zhuming, Ma, Chengbang, Zhou, Mei, Chen, Xiaoling, Siu, Shirley W. I., Chen, Tianbao, Wang, Lei, Kwok, Hang Fai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123395/ https://www.ncbi.nlm.nih.gov/pubmed/33925935 http://dx.doi.org/10.3390/ijms22094509

Ejemplares similares

In Vitro & In Vivo Studies on Identifying and Designing Temporin-1CEh from the Skin Secretion of Rana chensinensis as the Optimised Antibacterial Prototype Drug
por: Ye, Zhuming, et al.
Publicado: (2022)

Bioevaluation of Ranatuerin-2Pb from the Frog Skin Secretion of Rana pipiens and Its Truncated Analogues
por: Zhou, Xiaowei, et al.
Publicado: (2019)

Discovery of a Novel Antimicrobial Peptide, Temporin-PKE, from the Skin Secretion of Pelophylax kl. esculentus, and Evaluation of Its Structure-Activity Relationships
por: Lin, Yaxian, et al.
Publicado: (2022)

Biological Activities of Cationicity-Enhanced and Hydrophobicity-Optimized Analogues of an Antimicrobial Peptide, Dermaseptin-PS3, from the Skin Secretion of Phyllomedusa sauvagii
por: Tan, Yining, et al.
Publicado: (2018)

Evaluation of the bioactivity of a mastoparan peptide from wasp venom and of its analogues designed through targeted engineering
por: Chen, Xiaoling, et al.
Publicado: (2018)

Evaluating the Bioactivity of a Novel Broad-Spectrum Antimicrobial Peptide Brevinin-1GHa from the Frog Skin Secretion of Hylarana guentheri and Its Analogues
por: Chen, Qi, et al.
Publicado: (2018)

Bioevaluation and Targeted Modification of Temporin-FL From the Skin Secretion of Dark-Spotted Frog (Pelophylax nigromaculatus)
por: Wang, Wenjie, et al.
Publicado: (2021)

Discovery and analysis of a novel antimicrobial peptide B1AW from the skin secretion of Amolops wuyiensis and improving the membrane-binding affinity through the construction of the lysine-introduced analogue
por: Qin, Haixin, et al.
Publicado: (2023)

Broad-Spectrum Antimicrobial Activity and Improved Stability of a D-Amino Acid Enantiomer of DMPC-10A, the Designed Derivative of Dermaseptin Truncates
por: Zai, Yu, et al.
Publicado: (2020)

Structure–Activity Relationship and Molecular Docking of a Kunitz-Like Trypsin Inhibitor, Kunitzin-AH, from the Skin Secretion of Amolops hainanensis
por: Chen, Yuqing, et al.
Publicado: (2021)

A Novel Dermaseptin Isolated from the Skin Secretion of Phyllomedusa tarsius and Its Cationicity-Enhanced Analogue Exhibiting Effective Antimicrobial and Anti-Proliferative Activities
por: Li, Miaoran, et al.
Publicado: (2019)

Targeted Modification and Structure-Activity Study of GL-29, an Analogue of the Antimicrobial Peptide Palustrin-2ISb
por: Liu, Siyan, et al.
Publicado: (2022)

First-in-Class Cyclic Temporin L Analogue: Design, Synthesis, and Antimicrobial Assessment
por: Bellavita, Rosa, et al.
Publicado: (2021)

Evaluation of the Antimicrobial Properties of a Natural Peptide from Vespa mandarinia Venom and Its Synthetic Analogues as a Possible Route to Defeat Drug-Resistant Microbes
por: Zhang, Jin, et al.
Publicado: (2022)

Temporin B Forms Hetero-Oligomers with Temporin L, Modifies Its Membrane Activity, and Increases the Cooperativity of Its Antibacterial Pharmacodynamic Profile
por: Ferguson, Philip M., et al.
Publicado: (2022)

The Bactericidal Activity of Temporin Analogues Against Methicillin Resistant Staphylococcus aureus
por: Golda, Anna, et al.
Publicado: (2019)

Interaction of Temporin-L Analogues with the E. coli FtsZ Protein
por: Di Somma, Angela, et al.
Publicado: (2021)

Modification and Targeted Design of N-Terminal Truncates Derived from Brevinin with Improved Therapeutic Efficacy
por: He, Haoyang, et al.
Publicado: (2020)

Broad-Spectrum Antiviral Activity of the Amphibian Antimicrobial Peptide Temporin L and Its Analogs
por: Zannella, Carla, et al.
Publicado: (2022)

Exploration of the Structure–Function Relationships of a Novel Frog Skin Secretion-Derived Bioactive Peptide, t-DPH1, through Use of Rational Design, Cationicity Enhancement and In Vitro Studies
por: Qin, Haixin, et al.
Publicado: (2021)

Modification Strategy of D-leucine Residue Addition on a Novel Peptide from Odorrana schmackeri, with Enhanced Bioactivity and In Vivo Efficacy
por: Yao, Aifang, et al.
Publicado: (2021)

Structure–activity relationship of an antimicrobial peptide, Phylloseptin-PHa: balance of hydrophobicity and charge determines the selectivity of bioactivities
por: Liu, Yuzhang, et al.
Publicado: (2019)

Evaluating the Bioactivity of a Novel Antimicrobial and Anticancer Peptide, Dermaseptin-PS4(Der-PS4), from the Skin Secretion of Phyllomedusa sauvagii
por: Chen, Dong, et al.
Publicado: (2019)

Temporin-SHa and Its Analogs as Potential Candidates for the Treatment of Helicobacter pylori
por: Olleik, Hamza, et al.
Publicado: (2019)

Antimicrobial Activity of a Lipidated Temporin L Analogue against Carbapenemase-Producing Klebsiella pneumoniae Clinical Isolates
por: Roscetto, Emanuela, et al.
Publicado: (2021)

Identification and Characterisation of the Antimicrobial Peptide, Phylloseptin-PT, from the Skin Secretion of Phyllomedusa tarsius, and Comparison of Activity with Designed, Cationicity-Enhanced Analogues and Diastereomers
por: Gao, Yitian, et al.
Publicado: (2016)

Discovery of two skin-derived dermaseptins and design of a TAT-fusion analogue with broad-spectrum antimicrobial activity and low cytotoxicity on healthy cells
por: Zhu, Haohao, et al.
Publicado: (2018)

A Review on Bradykinin-Related Peptides Isolated from Amphibian Skin Secretion
por: Xi, Xinping, et al.
Publicado: (2015)

Synergistic Antibacterial and Anti-Inflammatory Activity of Temporin A and Modified Temporin B In Vivo
por: Capparelli, Rosanna, et al.
Publicado: (2009)

Unveiling the mechanism of action of acylated temporin L analogues against multidrug-resistant Candida albicans
por: Bellavita, Rosa, et al.
Publicado: (2022)

Antibacterial and Antibiofilm Activity of Temporin-GHc and Temporin-GHd Against Cariogenic Bacteria, Streptococcus mutans
por: Zhong, Hengren, et al.
Publicado: (2019)

Pharmacological Effects of a Novel Bradykinin-Related Peptide (RR-18) from the Skin Secretion of the Hejiang Frog (Ordorrana hejiangensis) on Smooth Muscle
por: Zhou, Xiaowei, et al.
Publicado: (2020)

Enhanced Antimicrobial Activity of N-Terminal Derivatives of a Novel Brevinin-1 Peptide from The Skin Secretion of Odorrana schmackeri
por: Zhou, Xiaowei, et al.
Publicado: (2020)

Recent Advances and Challenges in Nanodelivery Systems for Antimicrobial Peptides (AMPs)
por: Tang, Ziyan, et al.
Publicado: (2021)

A novel antimicrobial peptide, Ranatuerin-2PLx, showing therapeutic potential in inhibiting proliferation of cancer cells
por: Chen, Xiaoling, et al.
Publicado: (2018)

Ex Vivo Smooth Muscle Pharmacological Effects of a Novel Bradykinin-Related Peptide, and Its Analogue, from Chinese Large Odorous Frog, Odorrana livida Skin Secretions
por: Xiang, Jie, et al.
Publicado: (2016)

Selection of antimicrobial frog peptides and temporin‐1DRa analogues for treatment of bacterial infections based on their cytotoxicity and differential activity against pathogens
por: Gaiser, Rogier A., et al.
Publicado: (2020)

Study on the Structure-Activity Relationship of an Antimicrobial Peptide, Brevinin-2GUb, from the Skin Secretion of Hylarana guentheri
por: Lin, Yaxian, et al.
Publicado: (2021)

Antifungal and Antibiofilm Activity of Cyclic Temporin L Peptide Analogues against Albicans and Non-Albicans Candida Species
por: Bellavita, Rosa, et al.
Publicado: (2022)

Brevinin-2GHk from Sylvirana guentheri and the Design of Truncated Analogs Exhibiting the Enhancement of Antimicrobial Activity
por: Chen, Guanzhu, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_nqo1j7drqfiajuje8euil06uce