Structural and conformational analysis of SARS CoV 2 N-CTD revealing monomeric and dimeric active sites during the RNA-binding and stabilization: Insights towards potential inhibitors for N-CTD

The advent of SARS-CoV-2 has become a universal health issue with no appropriate cure available to date. The coronavirus nucleocapsid (N) protein combines viral genomic RNA into a ribonucleoprotein and protects the viral genome from the host's nucleases. Structurally, the N protein comprises tw...

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Detalles Bibliográficos
Autores principales: Chauhan, Arushi, Avti, Pramod, Shekhar, Nishant, Prajapat, Manisha, Sarma, Phulen, Bhattacharyya, Anusuya, Kumar, Subodh, Kaur, Hardeep, Prakash, Ajay, Medhi, Bikash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123409/
https://www.ncbi.nlm.nih.gov/pubmed/34022485
http://dx.doi.org/10.1016/j.compbiomed.2021.104495

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