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Overexpression of Isl1 under the Pax2 Promoter, Leads to Impaired Sound Processing and Increased Inhibition in the Inferior Colliculus
The LIM homeodomain transcription factor ISL1 is essential for the different aspects of neuronal development and maintenance. In order to study the role of ISL1 in the auditory system, we generated a transgenic mouse (Tg) expressing Isl1 under the Pax2 promoter control. We previously reported a prog...
Autores principales: | Chumak, Tetyana, Tothova, Diana, Filova, Iva, Bures, Zbynek, Popelar, Jiri, Pavlinkova, Gabriela, Syka, Josef |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123449/ https://www.ncbi.nlm.nih.gov/pubmed/33925933 http://dx.doi.org/10.3390/ijms22094507 |
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