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Mouse Models for Deciphering the Impact of Homologous Recombination on Tumorigenesis

SIMPLE SUMMARY: Homologous recombination (HR) is a DNA repair pathway essential to genome stability and mutations in many HR genes are correlated with cancer predisposition. Transgenic mouse models are critical to establish HR factors as tumor suppressor genes. However, investigating the effects of...

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Detalles Bibliográficos
Autores principales:	Matos-Rodrigues, Gabriel, Martini, Emmanuelle, Lopez, Bernard S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123484/ https://www.ncbi.nlm.nih.gov/pubmed/33923105 http://dx.doi.org/10.3390/cancers13092083

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